Evidence map›Paper›PMID 36557087›Full record

ArticleMembranes2022

Arginine Homopeptide of 11 Residues as a Model of Cell-Penetrating Peptides in the Interaction with Bacterial Membranes.

Mónica Aróstica, Roberto Rojas, Luis Felipe Aguilar, Patricio Carvajal-Rondanelli, Fernando Albericio, Fanny Guzmán, Constanza Cárdenas

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Mónica ArósticaDoctorado en Biotecnología, Pontificia Universidad Católica de Valparaíso y Universidad Técnica Federico Santa María, Valparaíso 2373223, Chile.
Roberto RojasFacultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Sede Los Castaños, 7 Norte 1348, Viña del Mar 2531098, Chile.
Luis Felipe AguilarInstituto de Química, Pontificia Universidad Católica de Valparaíso, Av. Universidad 330, Valparaíso 2373223, Chile.ORCID 0000-0002-6038-3475
Patricio Carvajal-RondanelliEscuela de Alimentos, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, Waddington 716, Valparaíso 2360100, Chile.ORCID 0000-0003-4359-1448
Fernando AlbericioDepartment of Organic Chemistry and CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, University of Barcelona, Martí i Franqués, 1, 08028 Barcelona, Spain.ORCID 0000-0002-8946-0462
Fanny GuzmánNúcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Av. Universidad 330, Valparaíso 2373223, Chile.ORCID 0000-0002-7829-0568
Constanza CárdenasNúcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Av. Universidad 330, Valparaíso 2373223, Chile.ORCID 0000-0002-3673-9320
Pontificia Universidad Católica de Valparaíso · CLBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESUniversity of the Americas · CL

Funding

Agencia Nacional de Investigación y Desarrollo Fondecyt 1210056Universidad Técnica Federico Santa María Incentive Program for Scientific Initiation (PIIC)
6 · The paper itself

Abstract

Cell-penetrating peptides rich in arginine are good candidates to be considered as antibacterial compounds, since peptides have a lower chance of generating resistance than commonly used antibiotics. Model homopeptides are a useful tool in the study of activity and its correlation with a secondary structure, constituting an initial step in the construction of functional heteropeptides. In this report, the 11-residue arginine homopeptide (R11) was used to determine its antimicrobial activity against

Indexed as

antibacterial assaysarginine homopeptidecircular dichroismmodel membrane interactionssecondary structure PPII

Identifiers

PMID36557087
PMCPMC9788509
OpenAlexW4309848881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.