Evidence map›Paper›PMID 36556455›Full record

ArticleLife (Basel, Switzerland)2022

Implementation of a Commercial Deep Learning-Based Auto Segmentation Software in Radiotherapy: Evaluation of Effectiveness and Impact on Workflow.

Lorenzo Radici, Silvia Ferrario, Valeria Casanova Borca, Domenico Cante, Marina Paolini, Cristina Piva, Laura Baratto, Pierfrancesco Franco, Maria Rosa La Porta

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lorenzo RadiciDepartment of Medical Physics, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Silvia FerrarioDepartment of Radiation Oncology, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Valeria Casanova BorcaDepartment of Medical Physics, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Domenico CanteDepartment of Radiation Oncology, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.ORCID 0000-0002-8155-6865
Marina PaoliniDepartment of Radiation Oncology, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Cristina PivaDepartment of Radiation Oncology, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Laura BarattoDepartment of Medical Physics, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.
Pierfrancesco FrancoDepartment of Translational Medicine (DIMET), 'Maggiore della Carità' University Hospital, University of Eastern Piedmont, 28100 Novara, Italy.ORCID 0000-0003-2276-0687
Maria Rosa La PortaDepartment of Radiation Oncology, ASL TO4, Ivrea Community Hospital, 10015 Ivrea, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper delineation of both target volumes and organs at risk is a crucial step in the radiation therapy workflow. This process is normally carried out manually by medical doctors, hence demanding timewise. To improve efficiency, auto-contouring methods have been proposed. We assessed a specific commercial software to investigate its impact on the radiotherapy workflow on four specific disease sites: head and neck, prostate, breast, and rectum. For the present study, we used a commercial deep learning-based auto-segmentation software, namely Limbus Contour (LC), Version 1.5.0 (Limbus AI Inc., Regina, SK, Canada). The software uses deep convolutional neural network models based on a U-net architecture, specific for each structure. Manual and automatic segmentation were compared on disease-specific organs at risk. Contouring time, geometrical performance (volume variation, Dice Similarity Coefficient-DSC, and center of mass shift), and dosimetric impact (DVH differences) were evaluated. With respect to time savings, the maximum advantage was seen in the setting of head and neck cancer with a 65%-time reduction. The average DSC was 0.72. The best agreement was found for lungs. Good results were highlighted for bladder, heart, and femoral heads. The most relevant dosimetric difference was in the rectal cancer case, where the mean volume covered by the 45 Gy isodose was 10.4 cm

Indexed as

artificial intelligenceauto segmentationcontouringdelineationradiation therapy

Identifiers

PMID36556455
PMCPMC9782080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.