Evidence map›Paper›PMID 36556439›Full record

ReviewLife (Basel, Switzerland)2022

Left Atrial Remodeling in Response to Aortic Valve Replacement: Pathophysiology and Myocardial Strain Analysis.

Matteo Lisi, Maria Concetta Pastore, Alessio Fiorio, Matteo Cameli, Giulia Elena Mandoli, Francesca Maria Righini, Luna Cavigli, Flavio D'Ascenzi, Marta Focardi, Andrea Rubboli and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Matteo LisiDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Maria Concetta PastoreDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7223-141X
Alessio FiorioDepartment of Cardiovascular Disease-AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Viale Randi 5, 48121 Ravenna, Italy.
Matteo CameliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Giulia Elena MandoliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Francesca Maria RighiniDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Luna CavigliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Flavio D'AscenziDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Marta FocardiDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Andrea RubboliDepartment of Cardiovascular Disease-AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Viale Randi 5, 48121 Ravenna, Italy.
Gianluca CampoCardiology Unit and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.
Sergio MondilloDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.
Michael Y HeneinInstitute of Public Health and Clinical Medicine and Heart Centre, Umeå University, 90187 Umeå, Sweden.
University of Siena · ITUniversity of Ferrara · ITOspedale "Santa Maria delle Croci" di Ravenna · ITUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe aortic stenosis (AS) is the most common valve disease in the elderly and is associated with poor prognosis if treated only medically. AS causes chronic pressure overload, concentric left ventricular (LV) hypertrophy, myocardial stiffness, and diastolic dysfunction. This adverse remodeling also affects the left atrium (LA), which dilates and develops myocardial fibrosis, with a reduction in intrinsic function and a consequent high risk of the development of atrial fibrillation. Speckle-tracking echocardiography is able to detect myocardial dysfunction before other conventional parameters, such as LV ejection fraction, and also predict clinical outcomes. This review aims at describing LV and LA remodeling in AS and before and after aortic valve replacement and the usefulness of myocardial strain analysis in this clinical setting.

Indexed as

aortic stenosisleft atrial strainremodellingreplacementspeckle tracking

Identifiers

PMID36556439
PMCPMC9788515
OpenAlexW4312125475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.