Evidence map›Paper›PMID 36556283›Full record

ArticleJournal of personalized medicine2022

NLRP6 Induces Lung Injury and Inflammation Early in Brucella and Influenza Coinfection.

Bochang Shi, Hui Han, Huabin Li, Lingyun Tan, Xinyu Li, Keyu Wang, Bo Li, Wei He, Chongyu Tian, Fang Yan and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Bochang ShiInner Mongolia Key Laboratory of Molecular Biology, Inner Mongolia Medical University, Hohhot 010000, China.
Hui HanInner Mongolia Key Laboratory of Molecular Biology, Inner Mongolia Medical University, Hohhot 010000, China.
Huabin LiCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030600, China.
Lingyun TanSchool of Basic Medicine Sciences, Anhui Medical University, Hefei 230000, China.
Xinyu LiSchool of Basic Medicine Sciences, Anhui Medical University, Hefei 230000, China.
Keyu WangDepartment of Clinical Laboratory, The Second Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases, Beijing 100000, China.
Bo LiThe Fifth Medical Center of PLA General Hospital, Beijing 100000, China.
Wei HeSchool of Basic Medicine Sciences, Anhui Medical University, Hefei 230000, China.
Chongyu TianCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030600, China.
Fang YanCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong 030600, China.
Yanchun ShiInner Mongolia Key Laboratory of Molecular Biology, Inner Mongolia Medical University, Hohhot 010000, China.
Yuanqiang ZhengInner Mongolia Key Laboratory of Molecular Biology, Inner Mongolia Medical University, Hohhot 010000, China.
Zhongpeng ZhaoSchool of Basic Medicine Sciences, Anhui Medical University, Hefei 230000, China.
Anhui Medical University · CNShanxi Agricultural University · CNChinese PLA General Hospital · CNInner Mongolia Medical University · CNBeijing University of Chinese Medicine · CNQingdao Binhai University · CN

Funding

National Key Research and Development Program of China 2008ZXJ09003-001National Key Research and Development Program of China 2010CB530202National Key Research and Development Program of China 2019SWAQ05National Key Research and Development Program of China 2019YFC1200604National Natural Science Foundation of China 31172301National Natural Science Foundation of China 81871252National Natural Science Foundation of China 82000004Program of Natural Science Foundation of Inner Mongolia 201702097Program of Natural Science Foundation of Inner Mongolia 2022MS08011
6 · The paper itself

Abstract

(1) Background: With the resurgence of brucellosis epidemics in China in recent years, the chances of a brucella coinfection with other common respiratory pathogens, such as the influenza virus, have increased dramatically. However, little is known about the pathogenicity or the mechanisms of brucella and influenza coinfections. (2) Methods: To clarify the interventions in the early stages of lung damage due to brucella and influenza coinfections, we evaluated the effect of the coinfection on disease progression and mortality using a coinfection model in WT mice and NLRP6

Indexed as

BrucellacoinfectionIL-18Influenza A virusNLRP6

Identifiers

PMID36556283
PMCPMC9785007
OpenAlexW4311391909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.