Evidence map›Paper›PMID 36556271›Full record

ArticleJournal of personalized medicine2022

Virtual Surgical Planning, 3D-Printing and Customized Bone Allograft for Acute Correction of Severe Genu Varum in Children.

Giulia Alessandri, Leonardo Frizziero, Gian Maria Santi, Alfredo Liverani, Dante Dallari, Leonardo Vivarelli, Giovanni Luigi Di Gennaro, Diego Antonioli, Grazia Chiara Menozzi, Alessandro Depaoli and 2 more

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06380530 (Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06380530 narecruitingnot on this mapstarted 2024, after this paper: background citation

Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities

TypeinterventionalSponsorIstituto Ortopedico RizzoliRan2024 to 2029Enrolled100ConditionsMusculoskeletal Deformity, Musculoskeletal Abnormalities, Musculoskeletal DisorderArmsDeformity correction
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Giulia AlessandriDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0003-1586-4090
Leonardo FrizzieroDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0003-4809-3536
Gian Maria SantiDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0002-7966-6002
Alfredo LiveraniDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0002-3255-9381
Dante DallariReconstructive Orthopedic Surgery Innovative Techniques-Musculoskeletal Tissue Bank, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-0595-5477
Leonardo VivarelliReconstructive Orthopedic Surgery Innovative Techniques-Musculoskeletal Tissue Bank, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0003-1112-0262
Giovanni Luigi Di GennaroUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Diego AntonioliUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Grazia Chiara MenozziDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0003-3216-8046
Alessandro DepaoliUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Gino RoccaUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Giovanni TrisolinoUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-0361-9920
Istituto Ortopedico Rizzoli · ITUniversity of Bologna · IT

Funding

Italian Ministry of Health TI-RAMS/RCR-2021
6 · The paper itself

Abstract

Complex deformities of lower limbs are frequent in children with genetic or metabolic skeletal disorders. Early correction is frequently required, but it is technically difficult and burdened by complications and recurrence. Herein, we described the case of a 7-year-old girl affected by severe bilateral genu varum due to spondyloepiphyseal dysplasia. The patient was treated by patient-specific osteotomies and customized structural wedge allograft using Virtual Surgical Planning (VSP) and 3D-printed patient-specific instrumentation (PSI). The entire process was performed through an in-hospital 3D-printing Point-of-Care (POC). VSP and 3D-printing applied to pediatric orthopedic surgery may allow personalization of corrective osteotomies and customization of structural allografts by using low-cost in-hospital POC. However, optimal and definitive alignment is rarely achieved in such severe deformities in growing skeleton through a single operation.

Indexed as

3D-printingcutting guidein-hospitalosteotomypatient-specific instrumentspediatricpoint-of-carespondyloepiphyseal dysplasiastructural allograftVSP

Identifiers

PMID36556271
PMCPMC9783361
OpenAlexW4311232240

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.