Evidence map›Paper›PMID 36556178›Full record

ReviewJournal of personalized medicine2022

Direct-Acting Antivirals and the Risk of Hepatitis B Reactivation in Hepatitis B and C Co-Infected Patients: A Systematic Review and Meta-Analysis.

Joo Hyun Oh, Dong Ah Park, Min Jung Ko, Jeong-Ju Yoo, Sun Young Yim, Ji-Hyun Ahn, Dae Won Jun, Sang Bong Ahn

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 citations in OpenAlex.

  1. Sex Disparities in Hepatitis C Treatment Initiation: Role of Universal Access to DAA in France (ANRS FANTASIO 2).Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  2. [APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. [Accelerating the elimination of hepatitis B virus infection: expert recommendations for expanding prevention and treatment].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Joo Hyun OhDepartment of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul 01830, Republic of Korea.ORCID 0000-0002-9140-9498
Dong Ah ParkDivision of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency (NECA), Seoul 04933, Republic of Korea.
Min Jung KoDivision of Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency (NECA), Seoul 04933, Republic of Korea.
Jeong-Ju YooDepartment of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Republic of Korea.ORCID 0000-0002-7802-0381
Sun Young YimDepartment of Internal Medicine, Korea University Hospital, Seoul 02841, Republic of Korea.
Ji-Hyun AhnDepartment of Internal Medicine, Hanyang University College of Medicine, Guri 11923, Republic of Korea.
Dae Won JunDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.ORCID 0000-0002-2875-6139
Sang Bong AhnDepartment of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul 01830, Republic of Korea.ORCID 0000-0001-7419-5259
Eulji University · KRNational Evidenc- based healthcare Collaborating Agency · KRHanyang University · KRHanyang University Guri Hospital · KRKorea University Medical Center · KRSoonchunhyang University · KR

Funding

National Evidence-based Healthcare Collaborating Agency NC20-001
6 · The paper itself

Abstract

Hepatitis B (HBV) reactivation was observed to be more than 10% in patients receiving interferon-based therapy for hepatitis C (HCV) co-infection. At present, when direct-acting antiviral (DAA) has become the main treatment for HCV, there are few large-scale studies on the reactivation of HBV in these population. We studied HBV reactivation risk and prophylactic HBV treatment efficacy in HBV/HCV co-infected patients receiving DAA therapy. Relevant studies were selected from the Ovid-Medline, Ovid-EMBASE, Cochrane Central Register of Controlled Trials, KoreaMed, KMbase, and RISS databases through 4 September 2020. Data pooling was carried out using the random-effects method. We identified 39 articles with 119,484 patients with chronic (

Indexed as

direct–acting antiviralshepatitis B virushepatitis C virusreactivation

Identifiers

PMID36556178
PMCPMC9781230
OpenAlexW4310225795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.