Evidence map›Paper›PMID 36556103›Full record

ArticleJournal of clinical medicine2022

Minimal Extracorporeal Circulation and Microplegia in the Setting of Urgent Coronary Artery Bypass Grafting.

Luca Koechlin, Brigitta Gahl, Jules Miazza, Urs Zenklusen, Bejtush Rrahmani, Ion Vasiloi, David Santer, Denis Berdajs, Friedrich S Eckstein, Oliver Reuthebuch

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Luca KoechlinDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Brigitta GahlDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Jules MiazzaDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Urs ZenklusenDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Bejtush RrahmaniDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Ion VasiloiDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
David SanterDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.ORCID 0000-0003-4493-4326
Denis BerdajsDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Friedrich S EcksteinDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
Oliver ReuthebuchDepartment of Cardiac Surgery, University Hospital Basel, 4031 Basel, Switzerland.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed to analyse the performance of minimal invasive extracorporeal circulation (MiECC) concomitantly with Microplegia, in patients with recent myocardial infarction (MI) undergoing urgent coronary artery bypass grafting (CABG) surgery. Methods: We included patients with a recent MI (≤7 days) undergoing isolated CABG surgery using MiECC. The primary endpoint was a major cardiovascular or cerebrovascular event (MACCE). In a secondary analysis, we compared our institutional Microplegia concept with the use of a crystalloid single-shot cardioplegic solution. Results: In total, 139 patients (mean ± standard deviation (SD) age 66 ± 10 years) underwent urgent CABG surgery using Microplegia; 55% (n = 77) of the patients had an acute MI within 1−7 days preoperatively; 20% (n = 28) had an acute MI within 6−24 h; and 24% (n = 34) had an acute MI within <6 h preoperatively. The number of distal anastomoses was a geometric mean of 4 (95% confidence interval 3−4). The MACCE and in-hospital mortality were 7% (n = 10) and 1% (n = 2), respectively. The results were confirmed in a secondary analysis comparing Microplegia with crystalloid cardioplegic solution (n = 271). Conclusion: The use of MiECC with Microplegia in urgent CABG surgery is feasible and safe and provides a straight-forward intraoperative setting. Therefore, it can also be considered to retain the benefits of MiECC in urgent CABG surgery.

Indexed as

coronary artery bypass graftingmicroplegiaminimal extracorporeal circulation systemmyocardial infarctionmyocardial protectionperfusion

Identifiers

PMID36556103
PMCPMC9781499
OpenAlexW4312195746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.