Evidence map›Paper›PMID 36556078›Full record

ArticleJournal of clinical medicine2022

Diagnosing Sport-Related Flow Limitations in the Iliac Arteries Using Near-Infrared Spectroscopy.

Martijn van Hooff, Jem Arnold, Eduard Meijer, Paul Schreuder, Marta Regis, Lin Xu, Marc Scheltinga, Hans Savelberg, Goof Schep

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Martijn van HooffDepartment of Sports and Exercise, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0002-8976-3500
Jem ArnoldDepartment of Sports and Exercise, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0003-3908-9447
Eduard MeijerDepartment of Clinical Physics, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0002-4753-8671
Paul SchreuderDepartment of Sports and Exercise, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0003-3841-2281
Marta RegisDepartment of Mathematics and Computer Science, Eindhoven University of Technology, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.ORCID 0000-0003-4306-8673
Lin XuSchool of Information Science and Technology, Shanghai Tech University, 393 Middle Huaxia Road, Shanghai 201210, China.ORCID 0000-0001-5777-1496
Marc ScheltingaDepartment of Vascular Surgery, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0003-4924-6194
Hans SavelbergDepartment of Nutrition and Movement Science, NUTRIM School for Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-8864-2109
Goof SchepDepartment of Sports and Exercise, Máxima Medical Centre, De Run 4600, 5500 MB Veldhoven, The Netherlands.ORCID 0000-0003-0207-8066
Radboud University Nijmegen · NLEindhoven University of Technology · NLMaastricht University · NLShanghaiTech University · CNUniversity of British Columbia · CA

Funding

Netherlands Organisation for Health Research and Development 75020017
6 · The paper itself

Abstract

Background: A flow limitation in the iliac arteries (FLIA) in endurance athletes is notoriously difficult to diagnose with the currently available diagnostic tools. At present, a commonly used diagnostic measure is a decrease in ankle brachial index with flex hips (ABIFlexed) following a maximal effort exercise test. Near-infrared spectroscopy (NIRS) is a non-invasive technique that measures skeletal muscle oxygenation as reflected by the balance of O2 delivery from microvascular blood flow and O2 uptake by metabolic activity. Therefore, NIRS potentially serves as a novel technique for diagnosing FLIA. The purpose of this study is to compare the diagnostic accuracy of NIRS-derived absolute, amplitude, and kinetic variables in legs during and after a maximal exercise test with ABIFlexed. Methods: ABIFlexed and NIRS were studied in 33 healthy subjects and 201 patients with FLIA diagnosed with echo-Doppler. Results: After maximal exercise, NIRS kinetic variables, such as the half value time and mean response time, resulted in a range of 0.921 to 0.939 AUC for the diagnosis of FLIA when combined with ABIFlexed. Conversely, ABIFlexed measurements alone conferred significantly worse test characteristics (AUC 0.717, p < 0.001). Conclusions: NIRS may serve as a diagnostic adjunct in patients with possible FLIA.

Indexed as

endofibrosismaximal exercise testingmuscle oxygen saturationnear-infrared spectroscopy

Identifiers

PMID36556078
PMCPMC9786904
OpenAlexW4312210783

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.