Evidence map›Paper›PMID 36556010›Full record

ReviewJournal of clinical medicine2022

Treatment of Cesarean Scar Ectopic Pregnancy in China with Uterine Artery Embolization-A Systematic Review and Meta-Analysis.

Greg J Marchand, Ahmed Taher Masoud, Catherine Coriell, Hollie Ulibarri, Julia Parise, Amanda Arroyo, Sydnee Goetz, Carmen Moir, Atley Moberly, Malini Govindan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Advances in Treating Cesarean Scar Pregnancy: A Comprehensive Review of Techniques, Clinical Outcomes, and Fertility Preservation.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Pooled it
  2. Review
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  6. Review
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  8. Are the Risk Factors for Developing Type 1 and Type 2 Cesarean Scar Pregnancy Different?Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Greg J MarchandMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.ORCID 0000-0003-4724-9148
Ahmed Taher MasoudMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Catherine CoriellMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Hollie UlibarriMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Julia PariseMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Amanda ArroyoMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Sydnee GoetzMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Carmen MoirMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Atley MoberlyMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Malini GovindanMarchand Institute for Minimally Invasive Surgery, Mesa, AZ 85209, USA.
Allen Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cesarean scar ectopic pregnancy (CSP) is a rare form of ectopic pregnancy, and treatment of CSP with uterine artery embolization (UAE) is a novel approach. With increasing numbers of cesarean sections being performed annually, the incidence of this condition is likely to increase. The authors became aware of an unusually high number of published studies originating in mainland China regarding this unusual treatment and sought to perform a meta-analysis to provide comprehensive evidence on this novel practice.

methodsWe performed a thorough search and included all forms of quality studies on this topic that reported UAE as a part of first-line management of CSP. We included only studies originating in China. Ultimately, 37 studies were included for qualitative and quantitative synthesis of evidence. After screening retrieved records and extracting data from eligible studies, we pooled continuous data as a mean estimate and 95% confidence interval (CI), and dichotomous data as proportion and 95% CI.

resultsCSP patients treated with protocols including UAE had a mean time of 30 days for serum β-hCG normalization, 95% CI [26.816, 33.881]. They had a mean estimated intraprocedural blood loss of 4.19 ± 3.76 mL, a mean hospital stay of nine days, 95%CI [7.914, 9.876], and a success rate of 93.4%, 95%CI [0.918, 0.951]. The severe complication rate was 1.2%, 95%CI [0.008, 0.017].

conclusionUAE, in combination with other procedures is being used effectively for the treatment of CSP in China. Protocols including UAE have a success rate of approximately 93.4%, and a severe complication rate of approximately 1.2%. This data's utility is limited by vast differences in the studied protocols and questionable feasibility outside of China.

Indexed as

cesarean scarectopic pregnancyextrauterine pregnancyuterine artery embolization

Identifiers

PMID36556010
PMCPMC9783593
OpenAlexW4311392489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.