ReviewJournal of clinical medicine2022
Effects of Low-Load Blood Flow Restriction Resistance Training on Muscle Strength and Hypertrophy Compared with Traditional Resistance Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Does Protocol Matter for Repetition Volume? A Meta-Analytic Investigation of Volitional Failure Versus the Traditionally Used 75-Repetition Blood Flow Restriction Resistance Training.Sports medicine - open · 2025Pooled it
- Effect of blood-flow restrictedPeerJ · 2025Pooled it
- Effects of upper extremity blood flow restriction training on muscle strength and hypertrophy: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- Blood flow restriction combined with resistance training on muscle strength and thickness improvement in young adults: a systematic review, meta-analysis, and meta-regression.Frontiers in physiology · 2024Pooled it
- Personalized blood flow restriction training at variable occlusion pressures improves multisystem function in overweight and obese older women.European journal of applied physiology · 2026Trial
- Effects of a low-load multi-component training program with blood flow restriction versus the same program without blood flow restriction on muscle thickness and functional outcomes in physically inactive young adults: randomized controlled trial.Frontiers in physiology · 2026Trial
- Evaluating the effectiveness of blood flow restriction training in older adults: An overview of systematic reviews.Sports medicine and health science · 2026Review
- The effect of blood flow restriction resistance exercise on arm muscle strength and isokinetic contraction parameters.BMC sports science, medicine & rehabilitation · 2026Article
- The effect of blood flow restricted exercise on measures of health and physical fitness across all populations: An umbrella review and meta-meta-analysis.Sports medicine and health science · 2025Review
- Methodological Approach to Predicting Lower Limb Blood Flow Restriction Pressure Using Anthropometry and Hemodynamics.Life (Basel, Switzerland) · 2025Article
- The Effects of Blood Flow Restriction Exercise on Muscle-Brain Crosstalk: A Systematic Review.Muscles (Basel, Switzerland) · 2025Review
- Exploring Blood Flow Restriction Exercise Protocols for Elderly Populations: A Scoping Review of Cuff Pressure, Frequency, and Duration for Muscle Strength, Hypertrophy, and Functional Abilities Outcomes.Journal of clinical medicine · 2025Review
- Age-Related Differences in Adaptation of Lean Body Mass, Muscle Strength, and Performance Following 6 Weeks of Blood Flow Restriction Training in Young and Older Adults.Journal of frailty, sarcopenia and falls · 2025Article
- The Safety of Blood Flow Restriction Combined with Stepping Aerobic Exercise in Older Adults with Sarcopenia.Clinical interventions in aging · 2025Article
- Blood flow restriction training: a new approach for preventing and treating sarcopenia in older adults.Frontiers in physiology · 2025Review
- No Differences in Exercise Performance, Perceptual Response, or Safety Were Observed Among 3 Blood Flow Restriction Devices.Arthroscopy, sports medicine, and rehabilitation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is clinical interest in determining the effects of low-load blood flow restriction (LL-BFR) resistance training on muscle strength and hypertrophy compared with traditional high- and low-load (HL and LL) resistance training in healthy older adults and the influence of LL-BFR training cuff-pressure on these outcomes.
methodsA search was performed on the MEDLINE, PEDro, CINHAL, Web of Science, Science Direct, Scopus, and CENTRAL databases.
resultsThe analysis included 14 studies. HL resistance training produces a small increase in muscle strength (eight studies; SMD, -0.23 [-0.41; -0.05]) but not in muscle hypertrophy (six studies; (SMD, 0.08 [-0.22; 0.38]) when compared with LL-BFR resistance training. Compared with traditional LL resistance training, LL-BFR resistance training produces small-moderate increases in muscle strength (seven studies; SMD, 0.44 [0.28; 0.60]) and hypertrophy (two studies; SMD, 0.51 [0.06; 0.96]). There were greater improvements in muscle strength when higher cuff pressures were applied versus traditional LL resistance training but not versus HL resistance training.
conclusionsLL-BFR resistance training results in lower muscle strength gains than HL resistance training and greater than traditional LL resistance training in healthy adults older than 60 years. LL-BFR resistance training promotes a similar muscle hypertrophy to HL resistance training but is greater than that of traditional LL resistance training. Applying cuff pressures above the limb occlusion pressure could enhance the increases in muscle strength compared with traditional LL resistance training.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.