Evidence map›Paper›PMID 36555930›Full record

ArticleJournal of clinical medicine2022

Inflammaging and Blood Pressure Profiles in Late Life: The Screening for CKD among Older People across Europe (SCOPE) Study.

Lisanne Tap, Andrea Corsonello, Mirko Di Rosa, Paolo Fabbietti, Francesc Formiga, Rafael Moreno-González, Johan Ärnlöv, Axel C Carlsson, Harmke A Polinder-Bos, Regina E Roller-Wirnsberger and 12 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Lisanne TapDepartment of Internal Medicine, Section of Geriatric Medicine, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-2989-4063
Andrea CorsonelloItalian National Research Center on Aging (INRCA), 60124 Ancona, Italy.ORCID 0000-0002-7276-3256
Mirko Di RosaItalian National Research Center on Aging (INRCA), 60124 Ancona, Italy.ORCID 0000-0002-1862-4159
Paolo FabbiettiItalian National Research Center on Aging (INRCA), 60124 Ancona, Italy.ORCID 0000-0003-2130-3070
Francesc FormigaGeriatric Unit, Internal Medicine Department, Bellvitge University Hospital-IDIBELL-L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Rafael Moreno-GonzálezGeriatric Unit, Internal Medicine Department, Bellvitge University Hospital-IDIBELL-L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Johan ÄrnlövSchool of Health and Social Studies, Dalarna University, 791 31 Falun, Sweden.
Axel C CarlssonDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, 171 77 Stockholm, Sweden.
Harmke A Polinder-BosDepartment of Internal Medicine, Section of Geriatric Medicine, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-7458-725X
Regina E Roller-WirnsbergerDepartment of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-1273-6520
Gerhard H WirnsbergerDepartment of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Tomasz KostkaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, 90-549 Lodz, Poland.ORCID 0000-0003-0437-650X
Agnieszka GuligowskaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, 90-549 Lodz, Poland.ORCID 0000-0002-6928-3892
Rada Artzi-MedvedikDepartment of Nursing, The Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.ORCID 0000-0003-0695-8845
Ilan YehoshuaMaccabi Healthcare Services, Southern Region, Tel Aviv 69978, Israel.
Christian WeingartDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, 93049 Regensburg, Germany.
Cornel C SieberDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, 93049 Regensburg, Germany.
Pedro GilDepartment of Geriatric Medicine, Hospital Clinico San Carlos, 28040 Madrid, Spain.
Sara Lainez MartinezDepartment of Geriatric Medicine, Hospital Clinico San Carlos, 28040 Madrid, Spain.
Fabrizia LattanzioItalian National Research Center on Aging (INRCA), 60124 Ancona, Italy.
Francesco U S Mattace-RasoDepartment of Internal Medicine, Section of Geriatric Medicine, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-1688-6497
SCOPE Investigators

Funding

European Union Horizon 2020 program 634869
6 · The paper itself

Abstract

The neutrophil-to-lymphocyte ratio (NLR) is a marker for systemic inflammation. Since inflammation plays a relevant role in vascular aging, the aim of this study was to investigate whether NLR is associated with blood pressure profiles in older adults. This study was performed within the framework of the SCOPE study including 2461 outpatients aged 75 years and over. Mean blood pressure values, namely systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP) were investigated across tertiles of NLR. Change in blood pressure levels in 2 years of follow-up were compared across categories of baseline NLR. Data of 2397 individuals were used, of which 1854 individuals had hypertension. Mean values of blood pressure did not differ across categories of baseline NLR in individuals without hypertension. Individuals with hypertension with a high-range NLR had lower SBP and PP when compared to those in low-range NLR (mean difference SBP -2.94 mmHg,

Indexed as

blood pressurehypertensioninflammationneutrophil-to-lymphocyte ratioolder adultsvascular aging

Identifiers

PMID36555930
PMCPMC9785752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.