Evidence map›Paper›PMID 36555887›Full record

ArticleJournal of clinical medicine2022

The Impact of a CMV Infection on the Expression of Selected Immunological Parameters in Liver Tissue in Children with Biliary Atresia.

Maria Janowska, Joanna B Bierła, Magdalena Kaleta, Aldona Wierzbicka-Rucińska, Piotr Czubkowski, Ewelina Kanarek, Bożena Cukrowska, Joanna Pawłowska, Joanna Cielecka-Kuszyk

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Lack of association between cytomegalovirus infection and liver fibrosis in patients with biliary atresia after the Kasai procedure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Immunology of Biliary Atresia.Seminars in pediatric surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria JanowskaDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Joanna B BierłaDepartment of Pathomorphology, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.ORCID 0000-0002-5772-5091
Magdalena KaletaDepartment of Pathomorphology, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Aldona Wierzbicka-RucińskaDepartment of Biochemistry, Radioimmunology and Experimental Medicine, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.ORCID 0000-0002-9578-8894
Piotr CzubkowskiDepartment of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Ewelina KanarekHistocompatibility Laboratory, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Bożena CukrowskaDepartment of Pathomorphology, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.ORCID 0000-0001-6887-0094
Joanna PawłowskaDepartment of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Joanna Cielecka-KuszykDepartment of Pathomorphology, The Children's Memorial Health Institute, 04-730 Warsaw, Poland.
Children's Memorial Health Institute · PL

Funding

the Children's Memorial Health Institute (Warsaw, Poland) S154/2017
6 · The paper itself

Abstract

The pathogenesis of biliary atresia (BA) is still not clear. The aim of this study was to evaluate the expression of selected immunological parameters in liver tissue in BA children based on CMV/EBV infection status. Eight of thirty-one children with newly diagnosed BA were included in this prospective study and assigned to two groups (I with active infection, II without active or past infection). All studies were performed on surgical liver biopsies. To visualize CD8+ T cells and CD56 expression, immunohistochemical staining was performed. The viral genetic material in the studied groups was not found, but CMV infection significantly affected the number of CD8+ lymphocytes in both the portal area and the bile ducts. The average number of CD8+ cells per mm

Indexed as

biliary atresiacytomegaloviruscytotoxic T cells

Identifiers

PMID36555887
PMCPMC9781492
OpenAlexW4311858879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.