Evidence map›Paper›PMID 36555785›Full record

ArticleInternational journal of molecular sciences2022

Mannosylated Systems for Targeted Delivery of Antibacterial Drugs to Activated Macrophages.

Igor D Zlotnikov, Maksim A Vigovskiy, Maria P Davydova, Milan R Danilov, Uliana D Dyachkova, Olga A Grigorieva, Elena V Kudryashova

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Igor D ZlotnikovFaculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.ORCID 0000-0002-2497-0859
Maksim A VigovskiyMedical Research and Education Center, Institute for Regenerative Medicine, Lomonosov Moscow State University, 27/10, Lomonosovsky Ave., 119192 Moscow, Russia.ORCID 0000-0003-2103-8158
Maria P DavydovaFaculty of Medicine, Lomonosov Moscow State University, 27/1, Lomonosovsky Prosp., 119192 Moscow, Russia.
Milan R DanilovFaculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.
Uliana D DyachkovaMedical Research and Education Center, Institute for Regenerative Medicine, Lomonosov Moscow State University, 27/10, Lomonosovsky Ave., 119192 Moscow, Russia.
Olga A GrigorievaMedical Research and Education Center, Institute for Regenerative Medicine, Lomonosov Moscow State University, 27/10, Lomonosovsky Ave., 119192 Moscow, Russia.
Elena V KudryashovaFaculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.ORCID 0000-0002-9761-7757

Funding

Russian Science Foundation 22-24-00604
6 · The paper itself

Abstract

Macrophages are a promising target for drug delivery to influence macrophage-associated processes in the body, namely due to the presence of resistant microorganisms in macrophages. In this work, a series of mannosylated carriers based on mannan, polyethylenimine (PEI) and cyclodextrin (CD) was synthesized. The molecular architecture was studied using FTIR and

Indexed as

Drug Delivery SystemsMacrophagesAnimalsAnti-Bacterial AgentsDrug CarriersMannoseMoxifloxacinPolymersRatsAnti-Bacterial AgentsDrug CarriersMannoseMoxifloxacinPolymersadjuvantdrug delivery systemmacrophage uptakemannose receptorpharmacokinetics

Identifiers

PMID36555785
PMCPMC9787453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.