Evidence map›Paper›PMID 36555783›Full record

ArticleInternational journal of molecular sciences2022

mTOR Signaling Network in Cell Biology and Human Disease.

Jane J Yu, Elena A Goncharova

Abstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. mTOR Signaling: Recent Progress.International journal of molecular sciences · 2024
    Article
  8. Review
  9. Review
  10. Everolimus-induced hyperpermeability of endothelial cells causes lung injury.Experimental biology and medicine (Maywood, N.J.) · 2023
    Article
  11. Structural Insights into theInternational journal of molecular sciences · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jane J YuDepartment of Internal Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
Elena A GoncharovaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Lung Center, School of Medicine, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0001-7118-6752

Funding

HIPPO Signaling in Pulmonary Arterial HypertensionR01HL130261 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2016 to 2023
$3.5M
TSC2 Signaling in Pulmonary Arterial HypertensionR01HL113178 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2012 to 2021
$3.1M
National Institute of Health R01HL113178NHLBI NIH HHS R01 HL113178NHLBI NIH HHS R01 HL130261
6 · The paper itself

Abstract

The mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates multiple processes, including gene transcription, protein synthesis, ribosome biogenesis, autophagy, cell metabolism, and cell growth [...].

Indexed as

Signal TransductionTOR Serine-Threonine KinasesAutophagyHumansMechanistic Target of Rapamycin Complex 1Protein BiosynthesisMechanistic Target of Rapamycin Complex 1MTOR protein, humanTOR Serine-Threonine Kinases

Identifiers

PMID36555783
PMCPMC9787689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.