Evidence map›Paper›PMID 36555742›Full record

ArticleInternational journal of molecular sciences2022

Immobilization of Alcalase on Silica Supports Modified with Carbosilane and PAMAM Dendrimers.

María Sánchez-Milla, Ester Hernández-Corroto, Javier Sánchez-Nieves, Rafael Gómez, María Luisa Marina, María Concepción García, F Javier de la Mata

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

María Sánchez-MillaDepartamento de Química Orgánica y Química Inorgánica, Universidad de Alcalá, Ctra. Madrid-Barcelona Km. 33.600, Alcalá de Henares, 28871 Madrid, Spain.
Ester Hernández-CorrotoDepartamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.600, Universidad de Alcalá, Alcalá de Henares, 28871 Madrid, Spain.
Javier Sánchez-NievesDepartamento de Química Orgánica y Química Inorgánica, Universidad de Alcalá, Ctra. Madrid-Barcelona Km. 33.600, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0003-0410-2285
Rafael GómezDepartamento de Química Orgánica y Química Inorgánica, Universidad de Alcalá, Ctra. Madrid-Barcelona Km. 33.600, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0001-6448-2414
María Luisa MarinaInstituto de Investigación Química "Andrés M. del Río", Ctra. Madrid-Barcelona Km. 33.600, Universidad de Alcalá, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0002-5583-1624
María Concepción GarcíaInstituto de Investigación Química "Andrés M. del Río", Ctra. Madrid-Barcelona Km. 33.600, Universidad de Alcalá, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0002-3383-6176
F Javier de la MataDepartamento de Química Orgánica y Química Inorgánica, Universidad de Alcalá, Ctra. Madrid-Barcelona Km. 33.600, Alcalá de Henares, 28871 Madrid, Spain.ORCID 0000-0003-0418-3935
Universidad de Alcalá · ES

Funding

Comunidad de Madrid B2017/BMD-3703 (NANODENDMED II-CM)Comunidad de Madrid S2018/BAA-4393 (AVANSECAL-II-CM)Ministery of Science and Innovation PID2020-112924RB-I00Ministery of Science and Innovation PID2020-114891RB-I00
6 · The paper itself

Abstract

Enzyme immobilization is a powerful strategy for enzyme stabilization and recyclability. Materials covered with multipoint molecules are very attractive for this goal, since the number of active moieties to attach the enzyme increases with respect to monofunctional linkers. This work evaluates different dendrimers supported on silica to immobilize a protease enzyme, Alcalase. Five different dendrimers were employed: two carbosilane (CBS) dendrimers of different generations (SiO

Indexed as

DendrimersEnzymes, ImmobilizedPolyaminesSilanesSilicon DioxidecarbosilaneDendrimersEnzymes, ImmobilizedPAMAM StarburstPoly(amidoamine)PolyaminesSilanesSilicon Dioxidealcalasecarbosilane dendrimerenzyme immobilizationPAMAM dendrimersilica

Identifiers

PMID36555742
PMCPMC9783553
OpenAlexW4312195397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.