Evidence map›Paper›PMID 36555545›Full record

ArticleInternational journal of molecular sciences2022

Thymoquinone Suppresses Angiogenesis in DEN-Induced Hepatocellular Carcinoma by Targeting miR-1-3p.

Samer A Tadros, Yasmin M Attia, Nadine W Maurice, Sally A Fahim, Fatma M Abdelwahed, Samar Ibrahim, Osama A Badary

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. The important role of miR-1-3p in cancers.Journal of translational medicine · 2023
    Review
  12. Review
  13. Article
  14. Effect ofCurrent issues in molecular biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Samer A TadrosDepartment of Biochemistry, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 26 July Mehwar Road Intersection with Wahat Road, 6th of October City P.O. Box 12451, Egypt.ORCID 0000-0002-3577-954X
Yasmin M AttiaPharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo P.O. Box 11796, Egypt.ORCID 0000-0002-5085-2901
Nadine W MauriceDepartment of Biochemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo P.O. Box 11562, Egypt.ORCID 0000-0002-0525-753X
Sally A FahimDepartment of Biochemistry, School of Pharmacy, Newgiza University (NGU), Newgiza, Km 22 Cairo-Alexandria Desert Road, Giza P.O. Box 12577, Egypt.
Fatma M AbdelwahedMedical Biochemistry and Molecular Biology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo P.O. Box 11796, Egypt.
Samar IbrahimClinical Pharmacy Practice Department, Ahram Canadian University, 4th Industrial Zone, Banks Complex, 6th of October City P.O. Box 12451, Egypt.
Osama A BadaryClinical Pharmacy Practice Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo P.O. Box 12508, Egypt.
Cairo University · EGAhram Canadian University · EGAin Shams University · EGOctober University of Modern Sciences and Arts · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is characterized by its high vascularity and metastasis. Thymoquinone (TQ), the main bio-active constituent of

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsAnimalsBenzoquinonesGene Expression Regulation, NeoplasticMatrix Metalloproteinase 2Matrix Metalloproteinase 9RatsVascular Endothelial Growth Factor ABenzoquinonesMatrix Metalloproteinase 2Matrix Metalloproteinase 9MicroRNAsMIRN1 microRNA, ratthymoquinoneVascular Endothelial Growth Factor Aangiogenesisdiethylnitrosamineliver cancermiR-1-3pthymoquinoneTIMP3

Identifiers

PMID36555545
PMCPMC9781440
OpenAlexW4311511276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.