Evidence map›Paper›PMID 36555527›Full record

ArticleInternational journal of molecular sciences2022

Combined Micellar Liquid Chromatography Technique and QSARs Modeling in Predicting the Blood-Brain Barrier Permeation of Heterocyclic Drug-like Compounds.

Małgorzata Janicka, Anna Śliwińska, Małgorzata Sztanke, Krzysztof Sztanke

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Małgorzata JanickaDepartment of Physical Chemistry, Faculty of Chemistry, Institute of Chemical Science, Maria Curie-Skłodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-5884-704X
Anna ŚliwińskaDoctoral School of Quantitative and Natural Sciences, Maria Curie-Skłodowska University, 20-038 Lublin, Poland.ORCID 0000-0003-2223-3457
Małgorzata SztankeDepartment of Medical Chemistry, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0003-1576-097X
Krzysztof SztankeLaboratory of Bioorganic Compounds Synthesis and Analysis, Medical University of Lublin, 4A Chodźki Street, 20-093 Lublin, Poland.ORCID 0000-0002-1898-5245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantitative structure-activity relationship (QSAR) methodology was used to predict the blood-brain permeability (log

Indexed as

Blood-Brain BarrierQuantitative Structure-Activity RelationshipBiological TransportChromatography, LiquidMicellesMicellesheterocyclic drug-like compoundslipophilicitylog BBmicellar chromatographyQSARs

Identifiers

PMID36555527
PMCPMC9786067

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.