Evidence map›Paper›PMID 36555462›Full record

ArticleInternational journal of molecular sciences2022

Normal Pregnancy-Induced Islet Beta Cell Proliferation in Mouse Models That Are Deficient in Serotonin-Signaling.

Lotte Goyvaerts, Anica Schraenen, Katleen Lemaire, Peter In't Veld, Ilse Smolders, Luc Maroteaux, Frans Schuit

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Decoding serotonin: the molecular symphony behind depression.Frontiers in cellular neuroscience · 2025
    Review
  4. Review
  5. Beta-cell compensation and gestational diabetes.The Journal of biological chemistry · 2023
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lotte GoyvaertsGene Expression Unit, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.
Anica SchraenenGene Expression Unit, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.
Katleen LemaireGene Expression Unit, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.
Peter In't VeldDepartment of Pathology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Ilse SmoldersDepartment of Pharmaceutical Sciences, Research Group Experimental Pharmacology (EFAR), Center for Neurosciences (C4N), Vrije Universiteit Brussel, 1090 Brussels, Belgium.ORCID 0000-0003-2140-0751
Luc MaroteauxINSERM UMR-U1270, Institut du Fer à Moulin, Sorbonne Université Paris, 75006 Paris, France.
Frans SchuitGene Expression Unit, Department of Cellular and Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-3225-6695
KU Leuven · BEVrije Universiteit Brussel · BEInserm · FR

Funding

FWO Vlaanderen G0B2516N
6 · The paper itself

Abstract

During mouse pregnancy placental lactogens stimulate prolactin receptors on pancreatic islet beta cells to induce expression of the tryptophan hydroxylase

Indexed as

Insulin-Secreting CellsIslets of LangerhansAnimalsCell ProliferationFemaleMicePlacentaPregnancySerotoninTryptophan HydroxylaseSerotoninTryptophan Hydroxylasebeta cell proliferationpregnancyserotonin

Identifiers

PMID36555462
PMCPMC9779327
OpenAlexW4311358127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.