Evidence map›Paper›PMID 36555326›Full record

ArticleInternational journal of molecular sciences2022

High-Yield Production of Chimeric Hepatitis E Virus-Like Particles Bearing the M2e Influenza Epitope and Receptor Binding Domain of SARS-CoV-2 in Plants Using Viral Vectors.

Eugenia S Mardanova, Roman Y Kotlyarov, Maya D Stuchinskaya, Lyudmila I Nikolaeva, Gergana Zahmanova, Nikolai V Ravin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

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  11. Green Biologics: Harnessing the Power of Plants to Produce Pharmaceuticals.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eugenia S MardanovaInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0003-2148-7658
Roman Y KotlyarovInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-4387-2592
Maya D StuchinskayaN.F. Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health, 123098 Moscow, Russia.ORCID 0000-0001-8544-7482
Lyudmila I NikolaevaN.F. Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health, 123098 Moscow, Russia.ORCID 0000-0002-1323-5568
Gergana ZahmanovaDepartment of Plant Physiology and Molecular Biology, University of Plovdiv, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-7667-9924
Nikolai V RavinInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-1456-1832
Russian Academy of Sciences · RUMinistry of Health of the Russian Federation · RUPlovdiv University · BG

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2022-318
6 · The paper itself

Abstract

Capsid protein of Hepatitis E virus (HEV) is capable of self-assembly into virus-like particles (VLPs) when expressed in

Indexed as

Artificial Virus-Like ParticlesCapsid ProteinsHepatitis E virusAntigen PresentationCOVID-19EpitopesHumansNicotianaPlants, Genetically ModifiedRecombinant Fusion ProteinsRecombinant ProteinsSARS-CoV-2Viral Matrix ProteinsCapsid ProteinsEpitopesM-protein, influenza virusRecombinant Fusion ProteinsRecombinant ProteinsViral Matrix Proteinshepatitis E virusinfluenza A virusM2e peptideplant-produced vaccineRBD of SARS-CoV-2virus-like particle

Identifiers

PMID36555326
PMCPMC9779006
OpenAlexW4312123275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.