Evidence map›Paper›PMID 36555289›Full record

ArticleInternational journal of molecular sciences2022

3-Bromopyruvate Suppresses the Malignant Phenotype of Vemurafenib-Resistant Melanoma Cells.

Patrik da Silva Vital, Murilo Bonatelli, Marina Pereira Dias, Larissa Vedovato Vilela de Salis, Mariana Tomazini Pinto, Fátima Baltazar, Silvya Stuchi Maria-Engler, Céline Pinheiro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Purinergic P2X7R as a potential target for pancreatic cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Patrik da Silva VitalMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.ORCID 0000-0001-8390-6980
Murilo BonatelliMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.ORCID 0000-0002-7607-5119
Marina Pereira DiasMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.
Larissa Vedovato Vilela de SalisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.ORCID 0000-0002-5604-7444
Mariana Tomazini PintoMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.
Fátima BaltazarLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-1770-4544
Silvya Stuchi Maria-EnglerClinical Chemistry and Toxicology Department, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 04023-901, SP, Brazil.ORCID 0000-0003-4771-6041
Céline PinheiroMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, SP, Brazil.ORCID 0000-0002-4685-8534
Hospital de Câncer de Barretos · BRUniversidade de São Paulo · BRUniversity of Minho · PT

Funding

National Council for Scientific and Technological Development 309998/2019São Paulo Research Foundation 2015/25351-6São Paulo Research Foundation 2016/10821-0São Paulo Research Foundation 2016/13021-4São Paulo Research Foundation 2017/12620-4São Paulo Research Foundation 2019/07502-8São Paulo Research Foundation 2019/14189-4
6 · The paper itself

Abstract

(1)

Indexed as

MelanomaNeoplasm Recurrence, LocalCell Line, TumorDrug Resistance, NeoplasmHumansMutationPhenotypeProtein Kinase InhibitorsProto-Oncogene Proteins B-rafPyruvatesVemurafenibbromopyruvateProtein Kinase InhibitorsProto-Oncogene Proteins B-rafPyruvatesVemurafenibdrug resistancemelanomametabolismproto-oncogene protein B-rafvemurafenib

Identifiers

PMID36555289
PMCPMC9779063
OpenAlexW4312123581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.