Evidence map›Paper›PMID 36555281›Full record

ArticleInternational journal of molecular sciences2022

Cas9-Mediated Nanopore Sequencing Enables Precise Characterization of Structural Variants in

Dariush Skowronek, Robin A Pilz, Loisa Bonde, Ole J Schamuhn, Janne L Feldmann, Sabine Hoffjan, Christiane D Much, Ute Felbor, Matthias Rath

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. State-of-the-Art Molecular Genetics and Genomics in Germany.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Dariush SkowronekDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Robin A PilzDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Loisa BondeDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Ole J SchamuhnDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Janne L FeldmannDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Sabine HoffjanDepartment of Human Genetics, Ruhr-University, 44801 Bochum, Germany.
Christiane D MuchDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Ute FelborDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Matthias RathDepartment of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, 17475 Greifswald, Germany.
Universität Greifswald · DEUniversitätsmedizin Greifswald · DEMSH Medical School Hamburg – University of Applied Sciences and Medical University · DERuhr University Bochum · DE

Funding

Deutsche Forschungsgemeinschaft RA2876/2-2Research Network Molecular Medicine of the University Medicine Greifswald FOVB-2022-14University Medicine Greifswald - Gerhard Domagk program
6 · The paper itself

Abstract

Deletions in the

Indexed as

Carrier ProteinsDNA Copy Number VariationsNanopore SequencingCRISPR-Cas SystemsHumansKRIT1 ProteinMultiplex Polymerase Chain ReactionCarrier ProteinsCCM2 protein, humanKRIT1 ProteinKRIT1 protein, humancerebral cavernous malformationscopy number variantsCRISPR/Cas9long-read sequencingnanopore sequencingstructural variants

Identifiers

PMID36555281
PMCPMC9779250
OpenAlexW4312123493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.