Evidence map›Paper›PMID 36555181›Full record

ArticleInternational journal of molecular sciences2022

Aberrations in

Nela Kelam, Anita Racetin, Mirjana Polović, Benjamin Benzon, Marin Ogorevc, Katarina Vukojević, Merica Glavina Durdov, Ana Dunatov Huljev, Ivana Kuzmić Prusac, Davor Čarić and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Nela KelamDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.ORCID 0000-0002-6529-5474
Anita RacetinDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.
Mirjana PolovićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.
Benjamin BenzonDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.ORCID 0000-0003-3681-8499
Marin OgorevcDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.ORCID 0000-0002-3801-1026
Katarina VukojevićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.ORCID 0000-0003-2182-2890
Merica Glavina DurdovDepartment of Pathology, University Hospital Center Split, 21000 Split, Croatia.
Ana Dunatov HuljevDepartment of Pathology, University Hospital Center Split, 21000 Split, Croatia.
Ivana Kuzmić PrusacDepartment of Pathology, University Hospital Center Split, 21000 Split, Croatia.ORCID 0000-0001-5875-3839
Davor ČarićDepartment of Orthopaedics and Traumatology, University Hospital in Split, Spinciceva 1, 21000 Split, Croatia.ORCID 0000-0003-2999-4937
Fila RagužDepartment of Nephrology, University Hospital Center Mostar, 88000 Mostar, Bosnia and Herzegovina.
Sandra KostićDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.ORCID 0000-0001-6389-5604
University of Split · HRUniversity Clinical Hospital Mostar · BAUniversity of Mostar · BA

Funding

Croatian Science Foundation IP-06-2016-2575
6 · The paper itself

Abstract

This study aimed to explore the spatio-temporal expression patterns of congenital anomalies of kidney and urinary tract (CAKUT) candidate genes, Fibroblast Growth Factor Receptor 1 (FGFR1), Fibroblast Growth Factor Receptor 2 (FGFR2) and Receptor-Interacting Protein Kinase 5 (RIP5), in human fetal kidney development (CTRL) and kidneys affected with CAKUT. Human fetal kidneys from the 22nd to 41st developmental week (duplex, hypoplastic, dysplastic, and controls) were stained with antibodies and analyzed by epifluorescence microscopy and RT-qPCR. The effect of CAKUT candidate genes on kidney nephrogenesis and function is confirmed by statistically significant variations in the spatio-temporal expression patterns of the investigated markers. The nuclear localization of FGFR1, elevated expression score of

Indexed as

Receptor, Fibroblast Growth Factor, Type 1Receptor, Fibroblast Growth Factor, Type 2Receptor-Interacting Protein Serine-Threonine KinasesUrinary TractUrogenital AbnormalitiesHumansKidneyRNA, MessengerVesico-Ureteral RefluxDSTYK protein, humanFGFR1 protein, humanFGFR2 protein, humanReceptor, Fibroblast Growth Factor, Type 1Receptor, Fibroblast Growth Factor, Type 2Receptor-Interacting Protein Serine-Threonine KinasesRNA, MessengerCAKUTcongenital anomalies of the kidney and urinary tractFGFR1FGFR2kidney developmentRIP5

Identifiers

PMID36555181
PMCPMC9779456
OpenAlexW4311859391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.