Evidence map›Paper›PMID 36555164›Full record

ArticleInternational journal of molecular sciences2022

Efficient De Novo Biosynthesis of Heme by Membrane Engineering in

Zhexian Geng, Jinxia Ge, Wei Cui, Hui Zhou, Jieying Deng, Baocai Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Engineering a heme-dependent tryptophan hydroxylase pathway inSynthetic and systems biotechnology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Applications of the Whole-Cell System in the Efficient Biosynthesis of Heme.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhexian GengSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Jinxia GeSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Wei CuiSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.ORCID 0000-0002-3184-9512
Hui ZhouSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.ORCID 0000-0003-1503-6295
Jieying DengEngineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei 230601, China.
Baocai XuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Hefei University of Technology · CN

Funding

Baocai Xu 2021d06050001Hui Zhou 2021YFD2100804Jieying Deng 2108085QC148
6 · The paper itself

Abstract

Heme is of great significance in food nutrition and food coloring, and the successful launch of artificial meat has greatly improved the application of heme in meat products. The precursor of heme, 5-aminolevulinic acid (ALA), has a wide range of applications in the agricultural and medical fields, including in the treatment of corona virus disease 2019 (COVID-19). In this study,

Indexed as

COVID-19Escherichia coli ProteinsAminolevulinic AcidEscherichia coliFermentationHemeHumansMetabolic EngineeringAminolevulinic AcidEscherichia coli ProteinsHeme5-aminolevulinic acidEscherichia colihememembrane engineeringmetabolic engineering

Identifiers

PMID36555164
PMCPMC9779679
OpenAlexW4311853234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.