Evidence map›Paper›PMID 36555152›Full record

ArticleInternational journal of molecular sciences2022

Sphingosine as a New Antifungal Agent against

Fahimeh Hashemi Arani, Stephanie Kadow, Melanie Kramer, Simone Keitsch, Lisa Kirchhoff, Fabian Schumacher, Burkhard Kleuser, Peter-Michael Rath, Erich Gulbins, Alexander Carpinteiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Role of sphingolipids in the host-pathogen interaction.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2023
    Article
  5. Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility toInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fahimeh Hashemi AraniInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Stephanie KadowInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0001-6430-1230
Melanie KramerInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Simone KeitschInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Lisa KirchhoffInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0003-2015-275X
Fabian SchumacherInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0001-8703-3275
Burkhard KleuserInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.
Peter-Michael RathInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Erich GulbinsInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Alexander CarpinteiroInstitute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.

Funding

Deutsche Forschungsgemeinschaft GRK 2581Deutsche Forschungsgemeinschaft Gu335/38-1 and GRK 2098
6 · The paper itself

Abstract

This study investigated whether sphingosine is effective as prophylaxis against

Indexed as

Antifungal AgentsCandidaAnimalsAspergillusMiceMicrobial Sensitivity TestsSphingosineAntifungal AgentsSphingosineaspergilluscandidamitochondriapulmonary aspergillosissphingolipidssphingosineyeast

Identifiers

PMID36555152
PMCPMC9779773

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.