Evidence map›Paper›PMID 36555151›Full record

ArticleInternational journal of molecular sciences2022

Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter.

Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Tadashi Watabe, Kazuhiro Ooe, Takashi Yoshimura, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Koichi Fukase

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kazuko Kaneda-NakashimaCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.ORCID 0000-0001-6657-5059
Yoshifumi ShirakamiCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.ORCID 0000-0003-2352-9057
Tadashi WatabeCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.ORCID 0000-0001-8658-2395
Kazuhiro OoeCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.
Takashi YoshimuraCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.
Atsushi ToyoshimaCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.
Yang WangNishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa Wako, Saitama 351-0198, Japan.ORCID 0000-0002-7657-4751
Hiromitsu HabaNishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa Wako, Saitama 351-0198, Japan.
Koichi FukaseCore for Medicine and Science Collaborative Research and Education, Forefront Research Center, Osaka University Graduate School of Science, 1-1 Toyonaka, Osaka 560-0043, Japan.ORCID 0000-0001-8844-0710
The University of Osaka · JPRIKEN Nishina Center · JP

Funding

Japan Agency for Medical Research and Development JP20nk0101545h0001
6 · The paper itself

Abstract

This study confirmed the effect of sodium/iodine symporter (NIS) expression on existing drugs by in vitro and in vivo tests using cultured cell lines. The tumor growth inhibitory effect of sodium astatide ([

Indexed as

Iodine CompoundsSymportersThyroid NeoplasmsHumansIodine RadioisotopesIodine-131Iodine CompoundsIodine RadioisotopesSymporters[131I]NaI therapy[211At]NaAt therapyalpha therapyNIS expressionthyroid cancer

Identifiers

PMID36555151
PMCPMC9779414
OpenAlexW4311849719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.