Evidence map›Paper›PMID 36555136›Full record

ArticleInternational journal of molecular sciences2022

Influence of Single Deuterium Replacement on Frequency of Hydrogen Bond Dissociation in IFNA17 under the Highest Critical Energy Range.

Alexander Basov, Mikhail Drobotenko, Alexander Svidlov, Maria Bezhenar, Eugeny Gerasimenko, Arkadii Moiseev, Vadim Malyshko, Anna Dorohova, Andrey Drozdov, Mikhail Baryshev and 1 more

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In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander BasovDepartment of Fundamental and Clinical Biochemistry, Kuban State Medical University, 350063 Krasnodar, Russia.
Mikhail DrobotenkoDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.
Alexander SvidlovDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.
Maria BezhenarDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.
Eugeny GerasimenkoDepartment of Technology of Fats, Cosmetics, Commodity Science, Processes and Devices, Kuban State Technological University, 350072 Krasnodar, Russia.
Arkadii MoiseevScientific Department, Kuban State Agrarian University, 350004 Krasnodar, Russia.
Vadim MalyshkoDepartment of Fundamental and Clinical Biochemistry, Kuban State Medical University, 350063 Krasnodar, Russia.ORCID 0000-0003-1323-0828
Anna DorohovaDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.
Andrey DrozdovLaboratory of Environmental Mass Spectrometry, Institute of Analytical Instrumentation of the Russian Academy of Sciences, 198095 Saint-Petersburg, Russia.
Mikhail BaryshevDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.
Stepan DzhimakDepartment of Radiophysics and Nanotechnology, Kuban State University, 350040 Krasnodar, Russia.ORCID 0000-0003-2618-5376

Funding

Kuban Scientific Foundation Н-21.1/11the state assignment of the SSC RAS 122020100351-9
6 · The paper itself

Abstract

The effect of single substitutions of protium for deuterium in hydrogen bonds between pairs of nitrogenous bases on the open states occurrence probability at high critical breaking energies of these bonds has been studied. The study was carried out using numerical methods based on the angular mathematical model of DNA. The IFNA17 gene was divided into three approximately equal parts. A comparison of the open states occurrence probability in these parts of the gene was done. To improve the accuracy of the results, a special data processing algorithm was developed. The developed methods have shown their suitability for taking into account the occurrence of open states in the entire range of high critical energies. It has been established that single

Indexed as

HydrogenModels, TheoreticalDeuteriumDNAHydrogen BondingNucleotidesDeuteriumDNAHydrogenNucleotidesdeuteriumDNAdynamics of a double-stranded DNA moleculeopen statesrotational movements of nitrogenous bases

Identifiers

PMID36555136
PMCPMC9778762

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.