Evidence map›Paper›PMID 36554962›Full record

ArticleInternational journal of environmental research and public health2022

Association between Physical Activity Levels and Brain Volumes in Adults Visiting Radio-Imaging Center of Tertiary Care Hospital.

Deepika Raja, Sneha Ravichandran, Baskaran Chandrasekaran, Rajagopal Kadavigere, M G Ramesh Babu, Meshari Almeshari, Amjad R Alyahyawi, Yasser Alzamil, Ahmad Abanomy, Suresh Sukumar

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Physical activity mediates age differences in cognition among Tsimane forager-horticulturalists.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Deepika RajaDepartment of Medical Imaging Technology, MCHP, MAHE, Manipal 576104, India.ORCID 0000-0001-6208-3831
Sneha RavichandranDepartment of Medical Imaging Technology, MCHP, MAHE, Manipal 576104, India.ORCID 0000-0002-4421-038X
Baskaran ChandrasekaranDepartment of Exercise and Sports Sciences, MCHP, MAHE, Manipal 576104, India.ORCID 0000-0003-1439-9158
Rajagopal KadavigereDepartment of Radiodiagnosis and Imaging, KMC, MAHE, Manipal 576104, India.ORCID 0000-0003-3486-8740
M G Ramesh BabuDepartment of Basic Medical Sciences, MAHE, Manipal 576104, India.ORCID 0000-0001-8456-9330
Meshari AlmeshariDepartment of Diagnostic Radiology, College of Applied Medical Science, University of Hail, Ha'il 81442, Saudi Arabia.ORCID 0000-0001-7838-4081
Amjad R AlyahyawiDepartment of Diagnostic Radiology, College of Applied Medical Science, University of Hail, Ha'il 81442, Saudi Arabia.
Yasser AlzamilDepartment of Diagnostic Radiology, College of Applied Medical Science, University of Hail, Ha'il 81442, Saudi Arabia.ORCID 0000-0002-9478-850X
Ahmad AbanomyDepartment of Radiological Sciences, Department of Diagnostic Radiology, College of Applied Medical Science, King Saud University, P.O. Box 10219, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-9029-0368
Suresh SukumarDepartment of Medical Imaging Technology, MCHP, MAHE, Manipal 576104, India.ORCID 0000-0001-9345-9790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThere is evidence to support the favorable impact of physical activity (PA) on brain volume. However, the empirical evidence exploring the relationship between physical and sedentary behavior remains mixed. We aimed to explore the relationship between PA and sedentary behavior and brain volume.

methodsThe study sample (n = 150, mean age = 39.7 years) included patients interviewed with the International Physical Activity Questionnaire (IPAQ) who underwent an MRI brain scan. From the images obtained, we measured total intracranial, gray matter, and white matter volume along with the hippocampus, amygdala, parahippocampal gyrus, and posterior cingulate cortex (PCC). Multivariable linear regression analysis was done. RESULTS AND DISCUSSION: Left hippocampus and overall PA were positively and significantly associated (β = 0.71,

conclusionWe found a positive association between total PA and the left hippocampus, whereas vigorous PA showed a negative association with the left hippocampus.

Indexed as

ExerciseGray MatterAdultCerebral CortexHippocampusHumansMagnetic Resonance ImagingTertiary Care CentersAAL3Brain Sizebrain volumeMRIprolonged sittingsedentary behaviour

Identifiers

PMID36554962
PMCPMC9779605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.