Evidence map›Paper›PMID 36554582›Full record

ReviewInternational journal of environmental research and public health2022

Contrast Agents during Pregnancy: Pros and Cons When Really Needed.

Federica Perelli, Irene Turrini, Maria Gabriella Giorgi, Irene Renda, Annalisa Vidiri, Gianluca Straface, Elisa Scatena, Marco D'Indinosante, Laura Marchi, Marco Giusti and 13 more

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
  7. Article
  8. Article
  9. Preexisting Liver Disease and Pregnancy: Optimizing Care to Optimize Outcomes.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Review
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  16. First-in-human Evaluation of Safety and Dosimetry of [Molecular imaging and biology · 2025
    Article
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  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Federica PerelliAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.
Irene TurriniAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.ORCID 0000-0001-9428-4929
Maria Gabriella GiorgiAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.
Irene RendaDivision of Obstetrics and Gynecology, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, 50134 Florence, Italy.
Annalisa VidiriSchool of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Gianluca StrafaceObstetrics and Gynecology Unit, Policlinico Abano Terme, 35031 Abano Terme, Italy.
Elisa ScatenaAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.
Marco D'IndinosanteAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.
Laura MarchiAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.
Marco GiustiAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.
Antonio OlivaDepartment of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-7112-9096
Simone GrassiDepartment of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-2420-6658
Carmen De LucaTeratology Information Service, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Francesco CataniaDepartment of Obstetrics and Gynecology, Ospedale "Santa Maria Alla Gruccia", 52025 Montevarchi, Italy.
Giuseppe VizzielliDepartment of Medicinal Area (DAME) Clinic of Obstetrics and Gynecology, Santa Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0002-2424-2691
Stefano RestainoDepartment of Medicinal Area (DAME) Clinic of Obstetrics and Gynecology, Santa Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0002-7848-0329
Giuseppe GulloIVF Public Center, Azienda Ospedaliera Ospedali Riuniti (AOOR) Villa Sofia Cervello, University of Palermo, 90146 Palermo, Italy.ORCID 0000-0003-4269-4269
Georgios EleftheriouPoison Control Center and Teratology Information Service, Hospital Papa Giovanni XIII, 24127 Bergamo, Italy.
Alberto MatteiAzienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.
Fabrizio SignoreObstetrics and Gynecology Unit, Santo Eugenio Hospital, 00144 Rome, Italy.
Antonio LanzoneSchool of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Giovanni ScambiaSchool of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Anna Franca CavaliereSchool of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many clinical conditions require radiological diagnostic exams based on the emission of different kinds of energy and the use of contrast agents, such as computerized tomography (CT), positron emission tomography (PET), magnetic resonance (MR), ultrasound (US), and X-ray imaging. Pregnant patients who should be submitted for diagnostic examinations with contrast agents represent a group of patients with whom it is necessary to consider both maternal and fetal effects. Radiological examinations use different types of contrast media, the most used and studied are represented by iodinate contrast agents, gadolinium, fluorodeoxyglucose, gastrographin, bariumsulfate, and nanobubbles used in contrast-enhanced ultrasound (CEUS). The present paper reports the available data about each contrast agent and its effect related to the mother and fetus. This review aims to clarify the clinical practices to follow in cases where a radiodiagnostic examination with a contrast medium is indicated to be performed on a pregnant patient.

Indexed as

Contrast MediaTomography, X-Ray ComputedFemaleHumansMagnetic Resonance ImagingPositron-Emission TomographyPregnancyUltrasonographyContrast Mediacomputerized tomographycontrast mediaionizing radiationmagnetic resonance imagingpositron emission tomographypregnantradiodiagnosticultrasound

Identifiers

PMID36554582
PMCPMC9779218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.