Evidence map›Paper›PMID 36554305›Full record

ArticleInternational journal of environmental research and public health2022

5-Methyltetrahydrofolate Alleviates Memory Impairment in a Rat Model of Alzheimer's Disease Induced by D-Galactose and Aluminum Chloride.

Zhengduo Zhang, Hong Wu, Shaojun Qi, Yanjin Tang, Chuan Qin, Rui Liu, Jiacheng Zhang, Yiyao Cao, Xibao Gao

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Neuroprotective properties ofIBRO neuroscience reports · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The effect of azelaic acid on AlClActa neuropsychiatrica · 2024
    Article
  7. Article
  8. Biocompatible MgFeCOBioengineering (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhengduo ZhangDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0001-6372-0150
Hong WuDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Shaojun QiDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Yanjin TangDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Chuan QinDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Rui LiuDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Jiacheng ZhangDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Yiyao CaoZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Xibao GaoDepartment of Physical and Chemical Inspection, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0002-4855-9693
Shandong University · CNZhejiang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of 5-methyltetrahydrofolate (5-MTHF) on a rat model of Alzheimer's disease (AD) induced by D-galactose (D-gal) and aluminum chloride (AlCl

Indexed as

Alzheimer DiseaseAcetylcholinesteraseAluminum ChlorideAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalGalactoseHippocampusMaze LearningMemory DisordersOxidative StressRatsRats, WistarRNA, MessengerTetrahydrofolates5-methyltetrahydrofolateAcetylcholinesteraseAluminum ChlorideAmyloid beta-PeptidesAmyloid beta-Protein PrecursorGalactoseRNA, MessengerTetrahydrofolatesVascular Endothelial Growth Factor Aadfolic acidhuman riskratstoxicity assessment

Identifiers

PMID36554305
PMCPMC9779170
OpenAlexW4311853426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.