Evidence map›Paper›PMID 36554196›Full record

ArticleEntropy (Basel, Switzerland)2022

Compositional Sequence Generation in the Entorhinal-Hippocampal System.

Daniel C McNamee, Kimberly L Stachenfeld, Matthew M Botvinick, Samuel J Gershman

Open access · goldAbstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Cognitive maps as a medium for thought.Trends in cognitive sciences · 2026
    Review
  2. Episodic recombination and the role of time in mental travel.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Daniel C McNameeNeuroscience Programme, Champalimaud Research, 1400-038 Lisbon, Portugal.ORCID 0000-0001-9928-4960
Kimberly L StachenfeldGoogle DeepMind, London N1C 4DN, UK.
Matthew M BotvinickGoogle DeepMind, London N1C 4DN, UK.
Samuel J GershmanDepartment of Psychology and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-6546-3298
Google DeepMind (United Kingdom) · GBChampalimaud Foundation · PTHarvard University · US

Funding

National Science Foundation CCF-1231216Wellcome Trust 110257/Z/15/Z
6 · The paper itself

Abstract

Neurons in the medial entorhinal cortex exhibit multiple, periodically organized, firing fields which collectively appear to form an internal representation of space. Neuroimaging data suggest that this grid coding is also present in other cortical areas such as the prefrontal cortex, indicating that it may be a general principle of neural functionality in the brain. In a recent analysis through the lens of dynamical systems theory, we showed how grid coding can lead to the generation of a diversity of empirically observed sequential reactivations of hippocampal place cells corresponding to traversals of cognitive maps. Here, we extend this sequence generation model by describing how the synthesis of multiple dynamical systems can support compositional cognitive computations. To empirically validate the model, we simulate two experiments demonstrating compositionality in space or in time during sequence generation. Finally, we describe several neural network architectures supporting various types of compositionality based on grid coding and highlight connections to recent work in machine learning leveraging analogous techniques.

Indexed as

compositionalityentorhinal cortexgenerative modelshippocampus

Identifiers

PMID36554196
PMCPMC9778317
OpenAlexW4311850018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.