Evidence map›Paper›PMID 36554089›Full record

ArticleHealthcare (Basel, Switzerland)2022

Oral Anticoagulation in Patients with Chronic Kidney Disease and Non-Valvular Atrial Fibrillation: The FAERC Study.

Marco Montomoli, Lourdes Roca, Mariana Rivera, Raul Fernandez-Prado, Beatriz Redondo, Rosa Camacho, Cayetana Moyano, Saul Pampa, Angela Gonzalez, Juan Casas and 11 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 15 institutions in 1 country.

Marco MontomoliNephrology Department, Hospital Clínico Universitario de Valencia, Av. Blasco Ibañez 17, 46010 Valencia, Spain.ORCID 0000-0003-1412-6352
Lourdes RocaNephrology Department, Hospital Universitario de La Plana, 12540 Villarreal, Spain.
Mariana RiveraNephrology Department, Hospital Universitario Virgen de la Macarena, 41009 Sevilla, Spain.
Raul Fernandez-PradoNephrology Department, Hospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain.
Beatriz RedondoNephrology Department, Hospital Universitario de Cruces, 48903 Bilbao, Spain.
Rosa CamachoNephrology Department, Hospital Universitario Severo Ochoa, 28914 Leganes, Spain.ORCID 0000-0002-2634-9783
Cayetana MoyanoNephrology Department, Hospital Universitario Reina Sofía, 14004 Córdoba, Spain.
Saul PampaNephrology Department, Hospital Universitario Rey Juan Carlos, 28933 Móstoles, Spain.
Angela GonzalezNephrology Department, Hospital Universitario Gregorio Marañón, 28007 Madrid, Spain.
Juan CasasNephrology Department, Hospital Comarcal Francesc de Borja, 46702 Gandía, Spain.ORCID 0000-0002-8967-1577
Maria KislikovaNephrology Department, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.ORCID 0000-0002-8387-1607
Ana Sanchez HorrilloNephrology Department, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Alicia Cabrera CárdenaNephrology Department, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Borja QuirogaNephrology Department, Hospital Universitario de La Princesa, 28006 Madrid, Spain.ORCID 0000-0001-5730-1929
Cristina RabascoNephrology Department, Hospital Universitario Reina Sofía, 14004 Córdoba, Spain.
Sara PiquerasNephrology Department, Complejo Hospitalario Universitario de Albacete, 02006 Albacete, Spain.ORCID 0000-0002-5258-578X
Andrea SusoNephrology Department, Hospital Universitario Severo Ochoa, 28914 Leganes, Spain.
Javier RequeNephrology Department, Hospital General Universitario de Castellón, 12004 Castelló, Spain.ORCID 0000-0002-6470-0685
Juan VillaNephrology Department, Hospital Universitario de Badajoz, 06080 Badajoz, Spain.
Raquel OjedaNephrology Department, Hospital Universitario Reina Sofía, 14004 Córdoba, Spain.
David ArroyoNephrology Department, Hospital Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0003-4652-0311
Hospital Universitario de La Princesa · ESHospital Universitario Reina Sofía · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario Severo Ochoa · ESCentro de Implantología Cirugía Oral y Maxilofacial · ESComplejo Hospitalario Universitario de Albacete · ESHospital Clínico Universitario de Valencia · ESHospital Comarcal de Inca · ESHospital de Cruces · ESHospital General Universitari de Castelló · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario La Paz · ESHospital Universitario Rey Juan Carlos · ESHospital Universitario Virgen Macarena · ESMarqués de Valdecilla University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common arrhythmia in patients with chronic kidney disease (CKD), and its presence is associated with a higher risk of stroke and mortality. MATERIAL AND

methodsThe FAERC study performed a retrospective multicentre analysis of historical cohorts in which data were collected from arrhythmia diagnosis onwards.

resultsWe analysed a Spanish cohort of 4749 patients with CKD (mean eGFR 33.9 mL/min) followed up in the nephrology clinic, observing a 12.2% prevalence of non-valvular AF. In total, 98.6% of these patients were receiving anticoagulant treatment, mainly with coumarins (79.7%). Using direct-acting oral anticoagulants (DOACs) was associated with fewer cerebrovascular events than using acenocoumarol, but in contrast with other studies, we could not corroborate the association of risk of bleeding, coronary events, or death with a type of anticoagulant prescribed.

conclusionsAtrial fibrillation is highly prevalent in renal patients. Direct-acting anticoagulants seem to be associated with fewer ischemic-embolic complications, with no differences in bleeding, coronary events, or mortality rates.

Indexed as

atrial fibrillationchronic kidney diseasecoumarinsdirect-action anticoagulantshaemorrhageischemic strokemortalityprevalence

Identifiers

PMID36554089
PMCPMC9778700
OpenAlexW4312140629

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.