Evidence map›Paper›PMID 36553984›Full record

ArticleHealthcare (Basel, Switzerland)2022

Prescription Opioid Use among Patients with Chronic Noncancer Pain before and after the COVID-19 Outbreak in Taiwan: A Multicenter Prospective Observational Study.

Jia-Lin Chen, Shung-Tai Ho, Wei-Zen Sun, Yu-Chuan Tsai, Kuang-I Cheng, Yen-Chin Liu, Yi-Jer Hsieh, Yeong-Ray Wen, Po-Kai Wang, Chun-Sung Sung and 2 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Jia-Lin ChenDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Shung-Tai HoDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Wei-Zen SunDepartment of Anesthesiology, National Taiwan University Hospital, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0001-8543-2600
Yu-Chuan TsaiDepartment of Anesthesiology, Center of Pain Management, E-Da Cancer Hospital, School of Medicine, I-Shou University College of Medicine, Kaohsiung 82445, Taiwan.
Kuang-I ChengDepartment of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.
Yen-Chin LiuDepartment of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.ORCID 0000-0002-5247-1678
Yi-Jer HsiehDepartment of Anesthesiology, Changhua Christian Hospital, Changhua 50006, Taiwan.
Yeong-Ray WenDepartment of Anesthesiology, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan.
Po-Kai WangDepartment of Anesthesiology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.ORCID 0000-0003-0321-4699
Chun-Sung SungDepartment of Anesthesiology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Chun-Chang YehDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.ORCID 0000-0002-7706-5991
Tso-Chou LinDepartment of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.ORCID 0000-0003-0131-2586
Tri-Service General Hospital · TWKaohsiung Medical University · TWChanghua Christian Hospital · TWChina Medical University · TWI-Shou University · TWNational Taiwan University · TWTaipei Veterans General Hospital · TWTzu Chi University · TW

Funding

Taiwan Ministry of Science and Technology MOST107-2314-B-016-009
6 · The paper itself

Abstract

backgroundThe COVID-19 outbreak disrupted medical access for patients receiving chronic opioid therapy. This study investigated their prescription opioid dosages before and after the 2020 outbreak in Taiwan.

methodsA prospective questionnaire survey was conducted among registered outpatients receiving long-term opioids before July 2019 in Taiwan. The questionnaire included items from the Taiwanese Brief Pain Inventory and quality of life assessment. Follow-up surveys in outpatient departments through October 2020 were conducted to collect opioid prescription data.

resultsAfter a mean of 531 days, the questionnaire responses of 103 of the initial 117 respondents were reviewed. Daily opioid doses decreased for 31 respondents (30.1%), remained roughly equivalent (defined as ±2.5%) for 27 (26.2%), and increased for 45 (43.7%) after the first wave of the pandemic. The use of strong opioids and nonopioid medications did not significantly differ among the three groups, but less fentanyl patch use was noted in the decreased-dose group after the outbreak. More than 70% of the patients received daily high-dose opioids (≥90 morphine milligram equivalents); moreover, 60% reported constipation. No deaths due to opioid overdose occurred during the study period.

conclusionsThe COVID-19 outbreak in 2020 did not interrupt access to long-term opioid prescriptions for most registered patients with chronic pain in Taiwan. Less fentanyl patch use was observed in participants whose opioid dose was tapering.

Indexed as

chronic painCOVID-19noncanceropioidprescription

Identifiers

PMID36553984
PMCPMC9778017
OpenAlexW4311636636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.