Evidence map›Paper›PMID 36553647›Full record

ArticleGenes2022

Machine Learning Heuristics on Gingivobuccal Cancer Gene Datasets Reveals Key Candidate Attributes for Prognosis.

Tanvi Singh, Girik Malik, Saloni Someshwar, Hien Thi Thu Le, Rathnagiri Polavarapu, Laxmi N Chavali, Nidheesh Melethadathil, Vijayaraghava Seshadri Sundararajan, Jayaraman Valadi, P B Kavi Kishor and 1 more

Abstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tanvi SinghBioclues.org, Hyderabad 500072, India.
Girik MalikBioclues.org, Hyderabad 500072, India.
Saloni SomeshwarBioclues.org, Hyderabad 500072, India.
Hien Thi Thu LeMolecular Signaling Lab, Faculty of Medicine & Health Technology, Tampere University, 33100 Tampere, Finland.
Rathnagiri PolavarapuAmity Institute of Microbial Technology, Amity University, SP-1 Kant Kalwar, NH11C, RIICO Industrial Area, Rajasthan 303002, India.
Laxmi N ChavaliBioclues.org, Hyderabad 500072, India.
Nidheesh MelethadathilAmrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Clappana 690525, India.
Vijayaraghava Seshadri SundararajanBioclues.org, Hyderabad 500072, India.
Jayaraman ValadiBioclues.org, Hyderabad 500072, India.
P B Kavi KishorMNR Foundation for Research & Innovation, MNR Medical College and Hospital, Fasalwadi, Sangareddy, Hyderabad 502294, India.ORCID 0000-0002-9587-7547
Prashanth SuravajhalaBioclues.org, Hyderabad 500072, India.ORCID 0000-0002-8535-278X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed cancer detection is one of the common causes of poor prognosis in the case of many cancers, including cancers of the oral cavity. Despite the improvement and development of new and efficient gene therapy treatments, very little has been carried out to algorithmically assess the impedance of these carcinomas. In this work, from attributes or NCBI's oral cancer datasets, viz. (i) name, (ii) gene(s), (iii) protein change, (iv) condition(s), clinical significance (last reviewed). We sought to train the number of instances emerging from them. Further, we attempt to annotate viable attributes in oral cancer gene datasets for the identification of gingivobuccal cancer (GBC). We further apply supervised and unsupervised machine learning methods to the gene datasets, revealing key candidate attributes for GBC prognosis. Our work highlights the importance of automated identification of key genes responsible for GBC that could perhaps be easily replicated in other forms of oral cancer detection.

Indexed as

HeuristicsMouth NeoplasmsHumansMachine LearningOncogenesPrognosisdata mininggene prioritizationgenomic datasetsmachine learningoral cancer

Identifiers

PMID36553647
PMCPMC9777687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.