Evidence map›Paper›PMID 36553636›Full record

ArticleGenes2022

TWIST1 Plays Role in Expression of Stemness State Markers in ESCC.

Mohammad Hossein Izadpanah, Mohammad Mahdi Forghanifard

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mohammad Hossein IzadpanahDivision of Human Genetics, Immunology Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad 9196773117, Iran.
Mohammad Mahdi ForghanifardDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan 3671637849, Iran.ORCID 0000-0002-7691-6897
Islamic Azad University, Damghan Branch · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStemness markers play critical roles in the maintenance of key properties of embryonic stem cells (ESCs), including the pluripotency, stemness state, and self-renewal capacities, as well as cell fate decision. Some of these features are present in cancer stem cells (CSCs). TWIST1, as a bHLH transcription factor oncogene, is involved in the epithelial-mesenchymal transition (EMT) process in both embryonic and cancer development. Our aim in this study was to investigate the functional correlation between

methods

resultsEctopic expression of

conclusions

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaCell Line, TumorGenes, HomeoboxHumansNerve Tissue ProteinsNuclear ProteinsRNA-Binding ProteinsRNA, MessengerTwist-Related Protein 1MSI1 protein, humanNerve Tissue ProteinsNuclear ProteinsRNA-Binding ProteinsRNA, MessengerTWIST1 protein, humanTwist-Related Protein 1cancer stem cells (CSCs)EMTESCCself-renewalstem cell markerTWIST1

Identifiers

PMID36553636
PMCPMC9777594
OpenAlexW4311612253

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.