Evidence map›Paper›PMID 36553620›Full record

ArticleGenes2022

Genetic Polymorphisms of Cytochromes P450 in Finno-Permic Populations of Russia.

Murat Dzhaubermezov, Natalya Ekomasova, Rustam Mustafin, Lilia Gabidullina, Yuliya Galimova, Alfiya Nurgalieva, Yana Valova, Darya Prokofyeva, Elza Khusnutdinova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Murat DzhaubermezovFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.ORCID 0000-0003-1570-3174
Natalya EkomasovaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Rustam MustafinFederal State Educational Institution of Higher Education, Bashkir State Medical University, 450008 Ufa, Russia.
Lilia GabidullinaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Yuliya GalimovaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Alfiya NurgalievaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Yana ValovaFederal Institution of Science, Ufa Research Institute of Occupational Health and Human Ecology, 450106 Ufa, Russia.
Darya ProkofyevaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Elza KhusnutdinovaFederal State Educational Institution of Higher Education, Ufa University of Science and Technology, 450076 Ufa, Russia.
Ufa Institute of Chemistry · RUBashkir State Medical University · RUUfa Research Institute of Occupational Health and Human Ecology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytochrome P450 is an enzyme involved in the metabolism of phase 1 xenobiotics, toxins, endogenous hormones, and drugs, including those used in COVID-19 treatment. Cytochrome p450 genes are linked to the pathogenesis of some multifactorial traits and diseases, such as cancer, particularly prostate cancer, colorectal cancer, breast cancer, and cervical cancer. Genotyping was performed on 540 supposedly healthy individuals of 5 Finno-Permic populations from the territories of the European part of the Russian Federation. There was a statistically significant difference between Veps and most of the studied populations in the rs4986774 locus of the CYP2D6 gene; data on the rs3892097 locus of the CYP2D6 gene shows that Izhemsky Komis are different from the Mordovian and Udmurt populations.

Indexed as

Cytochrome P-450 CYP2D6Cytochrome P-450 Enzyme SystemHumansPolymorphism, GeneticRussiaCytochrome P-450 CYP2D6Cytochrome P-450 Enzyme SystemCYP1A1CYP2D6Finno-Permic populationspharmacogenetic markers

Identifiers

PMID36553620
PMCPMC9777976
OpenAlexW4311495144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.