Evidence map›Paper›PMID 36553607›Full record

ArticleGenes2022

Transcriptional Specificity Analysis of Testis and Epididymis Tissues in Donkey.

Mubin Yu, Xiaoyuan Zhang, Jiamao Yan, Jianhua Guo, Fali Zhang, Kexin Zhu, Shuqin Liu, Yujiang Sun, Wei Shen, Junjie Wang

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Unraveling the genetic and physiological potential of donkeys: insights from genomics, proteomics, and metabolomics approaches.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  3. Article
  4. First Molecular Detection and Genetic Characterization ofAnimals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mubin YuCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Xiaoyuan ZhangCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Jiamao YanCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Jianhua GuoJiaozhou Agricultural and Rural Bureau, Jiaozhou 266300, China.
Fali ZhangCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.ORCID 0000-0002-1193-2183
Kexin ZhuCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Shuqin LiuCollege of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China.
Yujiang SunCollege of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China.
Wei ShenKey Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao 266109, China.
Junjie WangCollege of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.ORCID 0000-0002-7145-5702
Qingdao Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Donkeys, with high economic value for meat, skin and milk production, are important livestock. However, the current insights into reproduction of donkeys are far from enough. To obtain a deeper understanding, the differential expression analysis and weighted gene co-expression network analysis (WGCNA) of transcriptomic data of testicular and epididymis tissues in donkeys were performed. In the result, there were 4313 differentially expressed genes (DEGs) in the two tissues, including 2047 enriched in testicular tissue and 2266 in epididymis tissue. WGCNA identified 1081 hub genes associated with testis development and 6110 genes with epididymal development. Next, the tissue-specific genes were identified with the above two methods, and the gene ontology (GO) analysis revealed that the epididymal-specific genes were associated with gonad development. On the other hand, the testis-specific genes were involved in the formation of sperm flagella, meiosis period, ciliary assembly, ciliary movement, etc. In addition, we found that eca-Mir-711 and eca-Mir-143 likely participated in regulating the development of epididymal tissue. Meanwhile, eca-Mir-429, eca-Mir-761, eca-Mir-200a, eca-Mir-191 and eca-Mir-200b potentially played an important role in regulating the development of testicular tissue. In short, these results will contribute to functional studies of the male reproductive trait in donkeys.

Indexed as

EpididymisTestisAnimalsEquidaeGene Expression ProfilingMaleSemendonkeyepididymistestistranscriptomeWGCNA

Identifiers

PMID36553607
PMCPMC9777602
OpenAlexW4312125460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.