Evidence map›Paper›PMID 36553568›Full record

ReviewGenes2022

Fatty Acid Metabolism in Endothelial Cell.

Bin Liu, Zhiyu Dai

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. [Research progress on the metabolic regulatory mechanisms of coronary collateral circulation].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
  3. Article
  4. Review
  5. Metabolic Cross Talk in the Tumor Microenvironment.Cancer treatment and research · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Endothelial metabolic zonation in the vascular network: a spatiotemporal blueprint for angiogenesis.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bin LiuDivision of Pulmonary, Critical Care and Sleep, University of Arizona, 475 N 5th Street, Phoenix, AZ 85004, USA.ORCID 0000-0003-0467-3678
Zhiyu DaiDivision of Pulmonary, Critical Care and Sleep, University of Arizona, 475 N 5th Street, Phoenix, AZ 85004, USA.ORCID 0000-0002-2945-7923
University of Arizona · US

Funding

Role of Endothelial SOX17 Deficiency in the Pathogenesis of Pulmonary HypertensionR01HL158596 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2022 to 2026
$2.3M
Role of Smooth Muscle Progenitor Cells in Obliterative Vascular Remodeling and PHR00HL138278 · NHLBI · UNIVERSITY OF ARIZONA · PI DAI, ZHIYU · 2019 to 2021
$747k
6 · The paper itself

Abstract

The endothelium is a monolayer of cells lining the inner blood vessels. Endothelial cells (ECs) play indispensable roles in angiogenesis, homeostasis, and immune response under normal physiological conditions, and their dysfunction is closely associated with pathologies such as cardiovascular diseases. Abnormal EC metabolism, especially dysfunctional fatty acid (FA) metabolism, contributes to the development of many diseases including pulmonary hypertension (PH). In this review, we focus on discussing the latest advances in FA metabolism in ECs under normal and pathological conditions with an emphasis on PH. We also highlight areas of research that warrant further investigation.

Indexed as

GlycolysisNeovascularization, PathologicEndothelial CellsFatty AcidsHumansLipid MetabolismFatty Acidsendotheliumglycolysislipidvascular biology

Identifiers

PMID36553568
PMCPMC9777652
OpenAlexW4311845635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.