Evidence map›Paper›PMID 36553328›Full record

ArticleChildren (Basel, Switzerland)2022

Palliative Sedation Therapy in Pediatrics: An Algorithm and Clinical Practice Update.

Andrea Cuviello, Liza-Marie Johnson, Kyle J Morgan, Doralina L Anghelescu, Justin N Baker

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Palliative care for children with central nervous system tumors: results of a Spanish multicenter study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea CuvielloSt. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Liza-Marie JohnsonSt. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-7124-979X
Kyle J MorganDepartment of Anesthesia, University of Tennessee Health Science Center, Memphis, TN 38105, USA.ORCID 0000-0002-2031-3851
Doralina L AnghelescuSt. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Justin N BakerSt. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-6584-6483
St. Jude Children's Research Hospital · USUniversity of Tennessee Health Science Center · US

Funding

American Lebanese Syrian Associated Charities N/A
6 · The paper itself

Abstract

Palliative sedation therapy (PST) is an important clinical intervention for pediatric patients with refractory symptoms and suffering during the end-of-life (EOL) period. Variations in PST implementation including medication selection, limited literature regarding feasibility in various clinical settings, particularly non-intensive care units, and lack of education on evolving definitions and ideal practices may all contribute to the current underutilization of this valuable resource. We therefore offer a clinical algorithm for identifying appropriate patients for PST, ensuring all other modalities for symptom management have been considered and/or optimized, and present a guideline for PST implementation that can be adapted and individualized based on institutional experience and resource availability. Furthermore, through case-based clinical scenarios, we demonstrate how to incorporate this algorithm into EOL practice.

Indexed as

dexmedetomidineend of lifepain managementpalliative carepalliative sedation therapypropofolsymptom management

Identifiers

PMID36553328
PMCPMC9776759
OpenAlexW4311053368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.