Evidence map›Paper›PMID 36553283›Full record

ArticleChildren (Basel, Switzerland)2022

Successful Eltrombopag Therapy in a Child with MYH9-Related Inherited Thrombocytopenia.

Giuseppe Lassandro, Francesco Carriero, Domenico Noviello, Valentina Palladino, Giovanni Carlo Del Vecchio, Maria Felicia Faienza, Paola Giordano

Open access · goldAbstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giuseppe LassandroAzienda Ospedaliero Universitaria Consorziale Policlinico-Giovanni XXIII, Pediatria Universitaria "B. Trambusti", 70126 Bari, Italy.
Francesco CarrieroInterdisciplinay Medicine Department, Pediatric Section, University of Bari "Aldo Moro", 70126 Bari, Italy.
Domenico NovielloInterdisciplinay Medicine Department, Pediatric Section, University of Bari "Aldo Moro", 70126 Bari, Italy.
Valentina PalladinoAzienda Ospedaliero Universitaria Consorziale Policlinico-Giovanni XXIII, Pediatria Universitaria "B. Trambusti", 70126 Bari, Italy.
Giovanni Carlo Del VecchioAzienda Ospedaliero Universitaria Consorziale Policlinico-Giovanni XXIII, Pediatria Universitaria "B. Trambusti", 70126 Bari, Italy.ORCID 0000-0001-5462-0027
Maria Felicia FaienzaAzienda Ospedaliero Universitaria Consorziale Policlinico-Giovanni XXIII, Pediatria Universitaria "B. Trambusti", 70126 Bari, Italy.ORCID 0000-0002-1899-8337
Paola GiordanoAzienda Ospedaliero Universitaria Consorziale Policlinico-Giovanni XXIII, Pediatria Universitaria "B. Trambusti", 70126 Bari, Italy.
Ospedale Pediatrico Giovanni XXIII · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited thrombocytopenias represents a heterogenous group of diseases characterized by a congenital reduction in the platelet count that could lead to a bleeding tendency. MYH9-related disorders are characterized by large platelets and congenital thrombocytopenia. Thrombopoietin-receptor agonists: eltrombopag and romiplostim are currently approved in many countries for the treatment of different forms of acquired thrombocytopenia, such as immune thrombocytopenia. We report, instead, the successful use of eltrombopag to treat inherited thrombocytopenia in a patient with an MHY9-related disease. This is the first report of a chronic use of eltrombopag to elevate platelets in MYH9-related disorders without side effects.

Indexed as

childreneltrombopagMYH9

Identifiers

PMID36553283
PMCPMC9776785
OpenAlexW4310211207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.