Evidence map›Paper›PMID 36553196›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Conventional Ameloblastoma. A Case Report with Microarray and Bioinformatic Analysis.

Emiliano Jurado-Castañeda, Carla Monserrat Ramírez-Martínez, Alejandro Alonso-Moctezuma, Jessica Tamara Páramo-Sánchez, Diana Ivette Rivera-Reza, Osmar Alejandro Chanes-Cuevas, César Luis Ortiz-Solís, Mario Alberto Téliz-Meneses, Oscar Rohel Hernández-Ortega, Marco Xavier Vizzuete-Bolaños and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Emiliano Jurado-CastañedaDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Carla Monserrat Ramírez-MartínezDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Alejandro Alonso-MoctezumaOral and Maxillofacial Surgery Specialty, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.ORCID 0000-0001-6265-6636
Jessica Tamara Páramo-SánchezDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Diana Ivette Rivera-RezaDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Osmar Alejandro Chanes-CuevasDental Biomaterials Laboratory, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
César Luis Ortiz-SolísDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Mario Alberto Téliz-MenesesMaxillofacial Surgery Department, General Hospital of Balbuena, Mexico City 15970, Mexico.
Oscar Rohel Hernández-OrtegaOral and Maxillofacial Surgery Specialty, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Marco Xavier Vizzuete-BolañosOral and Maxillofacial Surgery Specialty, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Patricio Olmedo-BastidasOral and Maxillofacial Surgery Specialty, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Luis Fernando Jacinto-AlemánDepartment of Oral Medicine and Pathology, Postgraduate Division, Dental School, National Autonomous University of Mexico, Mexico City 04510, Mexico.ORCID 0000-0002-0384-5581
Universidad Nacional Autónoma de México · MXHospital General de México · MX

Funding

National Autonomous University of Mexico PAPIIT IN226720
6 · The paper itself

Abstract

Ameloblastoma is a rare benign epithelial odontogenic neoplasm, but with great clinical implications, as despite its benignity and slow growth, most cases are locally aggressive with a significant recurrence rate. Histological, cellular, or molecular analyses of its pathogenesis have confirmed the complexity of this neoplasm. We present the case of a 20-year-old patient with a suggestive clinical and radiographic diagnosis of ameloblastoma. An incisional biopsy was obtained confirming the diagnosis of conventional ameloblastoma. Left hemimandibulectomy and plate reconstruction were performed. Histopathological analysis of the surgical specimen confirmed the conventional ameloblastoma with a plexiform pattern and significant areas of cystic degeneration and amyloid-like-like deposits. Additionally, a microarray was carried out with bioinformatic analysis for the enrichment, protein interaction, and determination of eight hub genes (CRP, BCHE, APP, AKT1, AGT, ACTC1, ADAM10, and APOA2) related to their pathogenesis.

Indexed as

ameloblastomabioinformaticshemimandibulectomymicroarray analysisodontogenic tumor

Identifiers

PMID36553196
PMCPMC9777305
OpenAlexW4312140610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.