ArticleDiagnostics (Basel, Switzerland)2022
Impact of an Electronic Alert in Combination with a Care Bundle on the Outcomes of Acute Kidney Injury.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis.Critical care (London, England) · 2025Pooled it
- Electronic Alert Systems for Patients With Acute Kidney Injury: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Automated Electronic Alert for the Care and Outcomes of Adults With Acute Kidney Injury: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Shifts in Acute Kidney Injury Trends Post-Alert System Implementation: A Retrospective Observational Cohort Study.Kidney medicine · 2026Article
- Predicting acute kidney injury in trauma using an extreme gradient boosting model.Clinical kidney journal · 2025Article
- Small cell carcinoma of the ovary, hypercalcaemic type causing an acute kidney injury.BMJ case reports · 2025Article
- Urinary exosomes as promising biomarkers for early kidney disease detection.American journal of clinical and experimental urology · 2025Review
- A global snapshot on health systems capacity for detection, monitoring, and management of acute kidney injury: A multinational study from the ISN-GKHA.PLOS global public health · 2024Article
- A Review of Electronic Early Warning Systems for Acute Kidney Injury.Advances in urology · 2024Review
- Care Bundle for Acute Kidney Injury in Cardiac Patients: A Cluster-Randomized Trial.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early diagnosis is essential for the appropriate management of acute kidney injury (AKI). We evaluated the impact of an electronic AKI alert together with a care bundle on the progression and mortality of AKI. This was a single-center prospective study that included AKI patients aged ≥ 18 years, whereas those in palliative care, nephrology, and transplantation departments were excluded. An AKI alert was issued in electronic medical records and a care bundle was suggested. A series of classes were administered to the multidisciplinary teams by nephrologists, and a clinical pharmacist audited prescriptions. Patients were categorized into pre-alert and post-alert groups. The baseline characteristics were comparable between the pre-alert (n = 1613) and post-alert (n = 1561) groups. The 30-day mortality rate was 33.6% in the entire cohort and was lower in the post-alert group (30.5% vs. 36.7%; p < 0.001). Age, pulmonary disease, malignancy, and ICU admission were associated with an increase in 30-day mortality. The electronic AKI alert together with a care bundle and a multidisciplinary education program was associated with a reduction in 30-day mortality in patients with AKI.
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