Evidence map›Paper›PMID 36553092›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Development of in House ELISAs to Detect Antibodies to SARS-CoV-2 in Infected and Vaccinated Humans by Using Recombinant S, S1 and RBD Proteins.

Aysun Yilmaz, Nuri Turan, Bekir Sami Kocazeybek, Harika Oyku Dinc, Hasan Emre Tali, Ozge Aydin, Hamid Besim Tali, Semaha Gul Yilmaz, Dildar Konukoglu, Sermin Borekci and 12 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 3 countries.

Aysun YilmazDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Nuri TuranDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Bekir Sami KocazeybekDepartment of Medical Microbiology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.
Harika Oyku DincDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Bezmialem Vakif University, Istanbul 34098, Turkey.ORCID 0000-0003-3628-7392
Hasan Emre TaliDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Ozge AydinDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Hamid Besim TaliDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Semaha Gul YilmazDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Dildar KonukogluDepartment of Biocehmistry, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.
Sermin BorekciDepartment of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.
Dashzeveg BoldDepartment of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-9113-7296
Gleyder Roman SosaDepartment of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Nejdiye GungorduDepartment of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.ORCID 0000-0002-4058-3154
Ilgim VardalogluDepartment of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul 34098, Turkey.ORCID 0000-0003-1839-0951
Nesrin GareayaghiSisli, Hamidiye Etfal Training and Research Hospiatal, Blood Center, Istanbul 34098, Turkey.
Mine GuzelBiruni Laboratories, Esentepe, Istanbul 34098, Turkey.
Ebru GunerBiruni Laboratories, Esentepe, Istanbul 34098, Turkey.
Jean-Remy SadeyenThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Pengxiang ChangThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
Munir IqbalThe Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.ORCID 0000-0001-5165-5339
Juergen A RichtDepartment of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-7308-5672
Huseyin YilmazDepartment of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, Hadimkoy, Istanbul 34098, Turkey.
Istanbul University-Cerrahpaşa · TRThe Pirbright Institute · GBKansas State University · USBezmiâlem Vakıf Üniversitesi · TR

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
Sex-specific effects of obestity on Influenza A virus infection and immunityP20GM130448 · NIGMS · KANSAS STATE UNIVERSITY · PI REVATHI GOVIND · 2020 to 2026
$15.8M
Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council BBS/E/I/00007039Biotechnology and Biological Sciences Research Council BBS/E/I/COV07001NIAID NIH HHS 75N93021C00016NIGMS NIH HHS P20 GM130448
6 · The paper itself

Abstract

(1) Background: The aim of this study was to produce in-house ELISAs which can be used to determine SARS-CoV-2-specific antibody levels directed against the spike protein (S), the S1 subunit of S and the receptor binding domain (RBD) of S in SARS-CoV-2 vaccinated and infected humans. (2) Methods: Three in-house ELISAs were developed by using recombinant proteins of SARS-CoV-2, namely the S, S1 and RBD proteins. Specificity and sensitivity evaluations of these tests were performed using sera from SARS-CoV-2-infected (

Indexed as

ELISAhumanRBDrecombinantSS1SARS-CoV-2Turkey

Identifiers

PMID36553092
PMCPMC9777145
OpenAlexW4311939384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.