Evidence map›Paper›PMID 36553050›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Radiation Exposure and Lifetime Attributable Risk of Cancer Incidence and Mortality from Low- and Standard-Dose CT Chest: Implications for COVID-19 Pneumonia Subjects.

Mandeep Garg, Vahid Karami, Javad Moazen, Thomas Kwee, Ashu Seith Bhalla, Daryoush Shahbazi-Gahrouei, Yu-Hsuan Joni Shao

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mandeep GargDepartment of Radiodiagnosis & Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-4714-6299
Vahid KaramiClinical Research Development Unite, Ganjavian Hospital, Dezful University of Medical Sciences, Dezful 6461653476, Iran.ORCID 0000-0003-1360-2054
Javad MoazenInfectious and Tropical Diseases Research Center, School of Medicine, Dezful University of Medical Sciences, Dezful 6461653480, Iran.
Thomas KweeDepartment of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Hanzeplein, 9700 Groningen, The Netherlands.
Ashu Seith BhallaDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
Daryoush Shahbazi-GahroueiDepartment of Medical Physics, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan 8174673461, Iran.ORCID 0000-0002-8538-1898
Yu-Hsuan Joni ShaoGraduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 106, Taiwan.ORCID 0000-0002-0757-1901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the novel coronavirus disease 2019 (COVID-19) outbreak, there has been an unprecedented increase in the acquisition of chest computed tomography (CT) scans. Nearly 616 million people have been infected by COVID-19 worldwide to date, of whom many were subjected to CT scanning. CT exposes the patients to hazardous ionizing radiation, which can damage the genetic material in the cells, leading to stochastic health effects in the form of heritable genetic mutations and increased cancer risk. These probabilistic, long-term carcinogenic effects of radiation can be seen over a lifetime and may sometimes take several decades to manifest. This review briefly describes what is known about the health effects of radiation, the lowest dose for which there exists compelling evidence about increased radiation-induced cancer risk and the evidence regarding this risk at typical CT doses. The lifetime attributable risk (LAR) of cancer from low- and standard-dose chest CT scans performed in COVID-19 subjects is also discussed along with the projected number of future cancers that could be related to chest CT scans performed during the COVID-19 pandemic. The LAR of cancer Incidence from chest CT has also been compared with those from other radiation sources, daily life risks and lifetime baseline risk.

Indexed as

cancerchestcomputed tomographyCOVID-19radiation risk

Identifiers

PMID36553050
PMCPMC9777015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.