Evidence map›Paper›PMID 36553021›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Value of CT Perfusion for Collateral Status Assessment in Patients with Acute Ischemic Stroke.

Haryadi Prasetya, Manon L Tolhuisen, Miou S Koopman, Manon Kappelhof, Frederick J A Meijer, Lonneke S F Yo, Geert J Lycklama Á Nijeholt, Wim H van Zwam, Aad van der Lugt, Yvo B W E M Roos and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Advances in Collateral Neuroimaging for Acute Ischemic Stroke: Redefining Time and Tissue Windows in the Reperfusion Era.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haryadi PrasetyaDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-8019-6458
Manon L TolhuisenDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-2695-1117
Miou S KoopmanDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-4709-0130
Manon KappelhofDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-5250-8955
Frederick J A MeijerDepartment of Radiology, Radboud UMC, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-5921-639X
Lonneke S F YoDepartment of Radiology, Catharina Hospital, 5623 EJ Eindhoven, The Netherlands.
Geert J Lycklama Á NijeholtDepartment of Radiology, Haaglanden Medical Center, 2512 VA The Hague, The Netherlands.
Wim H van ZwamDepartment of Radiology, Maastricht University Medical Center and Cardiovascular Research Institute, 6229 ER Maastricht, The Netherlands.
Aad van der LugtDepartment of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, 3015 GD Rotterdam, The Netherlands.
Yvo B W E M RoosDepartment of Neurology, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.
Charles B L M MajoieDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.
Ed T van BavelDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-8654-986X
Henk A MarqueringDepartment of Biomedical Engineering and Physics, Amsterdam UMC, Location AMC, 1105 AZ Amsterdam, The Netherlands.
On Behalf Of The Mr Clean Registry Investigators

Funding

Indonesia Endowment Fund for Education (LPDP), Ministry of Finance, Republic of Indonesia LPDP scholarship Program for Doctorate Students
6 · The paper itself

Abstract

Good collateral status in acute ischemic stroke patients is an important indicator for good outcomes. Perfusion imaging potentially allows for the simultaneous assessment of local perfusion and collateral status. We combined multiple CTP parameters to evaluate a CTP-based collateral score. We included 85 patients with a baseline CTP and single-phase CTA images from the MR CLEAN Registry. We evaluated patients' CTP parameters, including relative CBVs and tissue volumes with several time-to-maximum ranges, to be candidates for a CTP-based collateral score. The score candidate with the strongest association with CTA-based collateral score and a 90-day mRS was included for further analyses. We assessed the association of the CTP-based collateral score with the functional outcome (mRS 0-2) by analyzing three regression models: baseline prognostic factors (model 1), model 1 including the CTA-based collateral score (model 2), and model 1 including the CTP-based collateral score (model 3). The model performance was evaluated using C-statistic. Among the CTP-based collateral score candidates, relative CBVs with a time-to-maximum of 6-10 s showed a significant association with CTA-based collateral scores (

Indexed as

collateralsCTPischemic strokeperfusion

Identifiers

PMID36553021
PMCPMC9777468

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.