Evidence map›Paper›PMID 36552948›Full record

ArticleDiagnostics (Basel, Switzerland)2022

OCT Angiography Features in Diabetes Mellitus Type 1 and 2.

Giovanni William Oliverio, Alessandro Meduri, Gabriella De Salvo, Luigi Trombetta, Pasquale Aragona

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Optical coherence tomography angiography: a review of the current literature.The Journal of international medical research · 2023
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Giovanni William OliverioDepartment of Biomedical Science, Ophthalmology Clinic, University of Messina, 98124 Messina, Italy.ORCID 0000-0003-3127-9756
Alessandro MeduriDepartment of Biomedical Science, Ophthalmology Clinic, University of Messina, 98124 Messina, Italy.
Gabriella De SalvoOphthalmology Department, University Hospital Southampton, Southampton SO16 5YA, UK.ORCID 0000-0002-1185-6942
Luigi TrombettaDepartment of Biomedical Science, Ophthalmology Clinic, University of Messina, 98124 Messina, Italy.
Pasquale AragonaDepartment of Biomedical Science, Ophthalmology Clinic, University of Messina, 98124 Messina, Italy.ORCID 0000-0002-9582-9799
University of Messina · ITUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To study the foveal avascular zone (FAZ) and the vessel densities (VD) in diabetic patients using optical coherence tomography angiography (OCT-A) and inner retinal layer changes to compare patients affected by type 1 diabetes (DM1) and type 2 diabetes (DM2). Methods: Cross-sectional observational study involving 150 eyes of 150 patients with DM1, and 155 eyes of 155 patients with DM2 with diabetic retinopathy (DR). Retinal nerve fiber layer (RNFL) and Ganglion cell layer (GCL) were evaluated. OCT-A studied both FAZ and VD at the level of the superficial capillary plexus (SCP) and the deep capillary plexus (DCP). Results: A statistically significant difference in FAZ area and foveal VD measured at the SCP (p < 0.001) was noted between DM1 and DM2 groups when comparing patients with mild and moderate non-proliferative diabetic retinopathy (NPDR), while no differences were found in the severe NPDR and proliferative diabetic retinopathy (PDR) subgroups. Duration of diabetes and stage of DR were directly correlated with enlargement of FAZ area and inversely correlated with foveal VD measured at SCP. RNFL and GCL were not different between DM1 and DM2 groups. Conclusion: Changes in OCT-A parameters detected in FAZ area and VD of diabetic patients with different stages of DR may help to predict the risk for progression of the disease.

Indexed as

diabetes mellitus type 1diabetes mellitus type 2FAZOCT-angiographyvessel density

Identifiers

PMID36552948
PMCPMC9777069
OpenAlexW4309935871

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.