Evidence map›Paper›PMID 36552881›Full record

ArticleCells2022

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice.

Henna Jäntti, Minna Oksanen, Pinja Kettunen, Stella Manta, Lionel Mouledous, Hennariikka Koivisto, Johanna Ruuth, Kalevi Trontti, Hiramani Dhungana, Meike Keuters and 9 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 4 countries.

Henna JänttiA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
Minna OksanenA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
Pinja KettunenNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-3119-4499
Stella MantaCentre de Recherches sur la Cognition Animale (CRCA), Université de Toulouse, CNRS, UPS, CEDEX 09, 31062 Toulouse, France.
Lionel MouledousCentre de Recherches sur la Cognition Animale (CRCA), Université de Toulouse, CNRS, UPS, CEDEX 09, 31062 Toulouse, France.
Hennariikka KoivistoA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
Johanna RuuthInstitute of Clinical Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
Kalevi TronttiSleepWell Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-3797-8163
Hiramani DhunganaNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.
Meike KeutersNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0003-4216-1024
Isabelle WeertNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-2888-478X
Marja KoskuviNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-1646-9992
Iiris HovattaSleepWell Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Anni-Maija LindenDepartment of Pharmacology, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Claire RamponCentre de Recherches sur la Cognition Animale (CRCA), Université de Toulouse, CNRS, UPS, CEDEX 09, 31062 Toulouse, France.
Tarja MalmA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
Heikki TanilaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.
Jari KoistinahoNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.
Taisia RolovaNeuroscience Center, HILIFE, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-8869-593X
University of Helsinki · FIUniversity of Eastern Finland · FICentre National de la Recherche Scientifique · FRBroad Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAgingAmyloid beta-Protein PrecursorAnimalsAstrocytesHumansMaleMicePresenilin-1Spatial LearningAmyloid beta-PeptidesAmyloid beta-Protein PrecursorPresenilin-1PSEN1 protein, humanAlzheimer’s diseaseastrocytesexperimental transplantationiPSColigodendrocyte precursor cellspresenilin

Identifiers

PMID36552881
PMCPMC9776487
OpenAlexW4312195476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.