Evidence map›Paper›PMID 36552879›Full record

ArticleCells2022

Valerio Caputo, Domenica Megalizzi, Carlo Fabrizio, Andrea Termine, Luca Colantoni, Cristina Bax, Juliette Gimenez, Mauro Monforte, Giorgio Tasca, Enzo Ricci and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Valerio CaputoGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0002-3503-3318
Domenica MegalizziGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0001-9517-0165
Carlo FabrizioData Science Unit, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0002-7824-8423
Andrea TermineData Science Unit, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0003-4374-7430
Luca ColantoniGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.
Cristina BaxGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.
Juliette GimenezEpigenetics and Genome Reprogramming Laboratory, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0001-7682-7088
Mauro MonforteUnità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Giorgio TascaUnità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-0849-9144
Enzo RicciUnità Operativa Complessa di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Carlo CaltagironeDepartment of Clinical and Behavorial Neurology, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.
Emiliano GiardinaGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.
Raffaella CascellaGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.
Claudia StrafellaGenomic Medicine Laboratory-UILDM, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.ORCID 0000-0003-1334-0920
Fondazione Santa Lucia · ITUniversity of Rome Tor Vergata · ITAgostino Gemelli University Polyclinic · ITNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study describes a protocol for methylation analysis integrated with Machine Learning (ML) algorithms developed to classify Facio-Scapulo-Humeral Dystrophy (FSHD) subjects. The DNA methylation levels of two

Indexed as

Muscular Dystrophy, FacioscapulohumeralBiomarkersDNA MethylationHumansProtein Processing, Post-TranslationalBiomarkersbiomarkerD4Z4DNA methylationepigeneticsFSHDmachine learningneuromuscular diseases

Identifiers

PMID36552879
PMCPMC9777431
OpenAlexW4311884399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.