Evidence map›Paper›PMID 36552835›Full record

ReviewCells2022

The Biological Effect of Small Extracellular Vesicles on Colorectal Cancer Metastasis.

Xiaoxing Wang, Defa Huang, Jiyang Wu, Zhengzhe Li, Xiaomei Yi, Tianyu Zhong

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The biological role of extracellular vesicles in gastric cancer metastasis.Frontiers in cell and developmental biology · 2024
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaoxing WangThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Defa HuangThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Jiyang WuThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Zhengzhe LiThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Xiaomei YiThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.
Tianyu ZhongThe First School of Clinical Medicine, Gannan Medical University, Ganzhou 341000, China.ORCID 0000-0003-1934-0032
Gannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a malignancy that seriously threatens human health, and metastasis from CRC is a major cause of death and poor prognosis for patients. Studying the potential mechanisms of small extracellular vesicles (sEVs) in tumor development may provide new options for early and effective diagnosis and treatment of CRC metastasis. In this review, we systematically describe how sEVs mediate epithelial mesenchymal transition (EMT), reconfigure the tumor microenvironment (TME), modulate the immune system, and alter vascular permeability and angiogenesis to promote CRC metastasis. We also discuss the current difficulties in studying sEVs and propose new ideas.

Indexed as

Colorectal NeoplasmsExtracellular VesiclesHumansTumor Microenvironmentangiogenesiscolorectal cancermetastasissmall extracellular vesiclestumor microenvironment

Identifiers

PMID36552835
PMCPMC9777375
OpenAlexW4312194540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.