Evidence map›Paper›PMID 36552783›Full record

ArticleCells2022

Selective Menin Deletion in the Hippocampal CA1 Region Leads to Disruption of Contextual Memory in the

Anosha Kiran Ulfat, Shadab Batool, Fahad Iqbal, Naweed I Syed

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anosha Kiran UlfatHotchkiss Brain Institute (HBI), University of Calgary, Calgary, AB T2N 4N1, Canada.
Shadab BatoolHotchkiss Brain Institute (HBI), University of Calgary, Calgary, AB T2N 4N1, Canada.
Fahad IqbalHotchkiss Brain Institute (HBI), University of Calgary, Calgary, AB T2N 4N1, Canada.
Naweed I SyedHotchkiss Brain Institute (HBI), University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-6124-9745
University of Calgary · CA

Funding

CIHR
6 · The paper itself

Abstract

Cholinergic neuronal networks in the hippocampus play a key role in the regulation of learning and memory in mammals. Perturbations of these networks, in turn, underlie neurodegenerative diseases. However, the mechanisms remain largely undefined. We have recently demonstrated that an in vitro

Indexed as

CA1 Region, HippocampalMemoryProto-Oncogene ProteinsAnimalsGain of Function MutationHippocampusMammalsMiceMice, KnockoutSynapsesMen1 protein, mouseProto-Oncogene Proteinsalpha 7 nicotinic receptorsAVV viral transfectioncontextual fear conditioninghippocampuslearning and memoryMEN1 rescueneuronstamoxifen

Identifiers

PMID36552783
PMCPMC9776806
OpenAlexW4311156291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.