Evidence map›Paper›PMID 36552764›Full record

ArticleCells2022

Elevated Monoamine Oxidase-A in Anterior Cingulate of Post-Mortem Human Parkinson's Disease: A Potential Surrogate Biomarker for Lewy Bodies?

Jogeshwar Mukherjee, Reisha M Ladwa, Christopher Liang, Amina U Syed

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Increased Binding of [Synapse (New York, N.Y.) · 2026
    Article
  2. Article
  3. Synthesis and Evaluation of Radioiodinated [Journal of labelled compounds & radiopharmaceuticals · 2026
    Article
  4. Assessment of [Biomolecules · 2025
    Article
  5. [Biomolecules · 2025
    Article
  6. Article
  7. [Molecules (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Abnormal [Synapse (New York, N.Y.) · 2023
    Article
  10. Article
  11. Development of [Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jogeshwar MukherjeePreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0003-1009-877X
Reisha M LadwaPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
Christopher LiangPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
Amina U SyedPreclinical Imaging, Department of Radiological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
University of California, Irvine · US

Funding

PET Imaging Agents for Nicotinic a4b2 ReceptorsR01AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2007 to 2017
$2.6M
PET Imaging agents for a4b2 Nicotinic ReceptorsRF1AG029479 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHRISTIAN, BRADLEY T, MUKHERJEE, JOGESHWAR · 2019 to 2020
$2.2M
Evaluation of Monoamine Oxidase-A as a New Biomarker for Alzheimer's DiseaseR21AG079189 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MUKHERJEE, JOGESHWAR · 2022 to 2022
$432k
NIA NIH HHS NIA RF1 AG029479 and NIA R21 AG079189NIA NIH HHS R01 AG029479NIA NIH HHS R21 AG079189
6 · The paper itself

Abstract

Lewy bodies (LB) play a neuropathological role in Parkinson's disease (PD). Our goal was to evaluate LB using anti-ubiquitin immunohistochemistry (UIHC) and find correlations with monoamine oxidase-A (MAO-A) using imaging agent, [

Indexed as

Gyrus CinguliLewy BodiesParkinson DiseaseAgedAged, 80 and overBiomarkersHumansMonoamine OxidaseUbiquitinBiomarkersMonoamine Oxidasemonoamine oxidase A, humanUbiquitin[18F]FAZIN3autoradiographyfluorine-18fluoroethyl harmolLewy bodiesmonoamine oxidase-AParkinson’s diseasePETQuPathubiquitin

Identifiers

PMID36552764
PMCPMC9777299
OpenAlexW4312125438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.